Colombo, Giancarlo

GABAB Receptor

Colombo, Giancarlo - GABAB Receptor, ebook


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ISBN: 9783319460444
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Table of contents

1. A Brief History of the GABAB Receptor
Norman G. Bowery

Part I. Chemistry

2. Chemistry of GABAB Receptor Ligands: Focus on Agonists and Antagonists
Federico Corelli, Claudia Mugnaini

3. The Allosteric Modulation of the GABAB Receptor: A Medicinal Chemistry Perspective
Claudia Mugnaini, Federico Corelli

Part II. Molecular Biology, Biochemistry, & Physiology

4. Molecular Organization, Trafficking, and Degradation of the GABAB Receptor
Dietmar Benke, Karthik Balakrishnan, Khaled Zemoura

5. Distribution and Localization of the GABAB Receptor
M. Paola Castelli, Gian Luigi Gessa

6. Activation Mechanism and Allosteric Properties of the GABAB Receptor
Julie Kniazeff, Xavier Rovira, Philippe Rondard, Jean-Philippe Pin

7. Modulation of Neurotransmission by the GABAB Receptor
Sriharsha Kantamneni

8. GABAB Receptor Functions in the Mesolimbic Dopamine System
Arnaud L. Lalive, Christian Lüscher

Part III. Pharmacology

9. Drug Discrimination Studies for Investigations on the Mechanisms of Action of GABAB Receptor Ligands
Michelle G. Baladi, Lawrence P. Carter

10. Targeting the GABAB Receptor for the Treatment of Epilepsy
Krutika Joshi, Miguel Angel Cortez, O. Carter Snead

11. Targeting the GABAB Receptor for the Treatment of Pain
Sam J. Enna, Kenneth E. McCarson

12. Targeting the GABAB Receptor for the Treatment of Depression and Anxiety Disorders
Daniela Felice, Olivia F. O’Leary, John F. Cryan

13. Targeting the GABAB Receptor in Fragile X Syndrome and Autism Spectrum Disorders
Aileen Healy

14. Targeting the GABAB Receptor for the Treatment of Substance Use Disorder
Małgorzata Frankowska, Edmund Przegaliński, Małgorzata Filip

15. Targeting the GABAB Receptor for the Treatment of Alcohol Use Disorder
Roberta Agabio, Kimberly A. Leite-Morris, Giovanni Addolorato, Giancarlo Colombo

16. Targeting the GABAB Receptors for the Treatment of Gastroesophageal Reflux Disease and Chronic Cough
Anders Lehmann, L. Ashley Blackshaw, Brendan J. Canning

17. Baclofen: Therapeutic Use and Potential of the Prototypic GABAB Receptor Agonist
Norman G. Bowery

18. Allosteric Modulators: The New Generation of GABAB Receptor Ligands
Stephan Urwyler

19. GABAB Receptor Antagonists as Cognition Enhancers
Furhan Iqbal, Quratul Ane Gillani

Keywords: Biomedicine, Neurosciences, Neurology

Publication year
The Receptors
Page amount
20 pages
Medicine, Health Care, Mode
Printed ISBN

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