Systems Biology of Tumor Microenvironment

1. Image Analysis of the Tumor Microenvironment
Mark C. Lloyd, Joseph O. Johnson, Agnieszka Kasprzak, Marilyn M. Bui

2. Hypoxia in Gliomas: Opening Therapeutical Opportunities Using a Mathematical-Based Approach
Alicia Martı́nez-González, Gabriel F. Calvo, Jose M. Ayuso, Ignacio Ochoa, Luis J. Fernández, Víctor M. Pérez-García

3. Computer Simulations of the Tumor Vasculature: Applications to Interstitial Fluid Flow, Drug Delivery, and Oxygen Supply
Michael Welter, Heiko Rieger

4. Cell-ECM Interactions in Tumor Invasion
Xiuxiu He, Byoungkoo Lee, Yi Jiang

5. Circulating Tumor Cells: When a Solid Tumor Meets a Fluid Microenvironment
Katarzyna A. Rejniak

6. Modeling Proteolytically Driven Tumor Lymphangiogenesis
Georgios Lolas, Lasse Jensen, George C. Bourantas, Vasiliki Tsikourkitoudi, Konstantinos Syrigos

7. Positive Feedback Loops Between Inflammatory, Bone and Cancer Cells During Metastatic Niche Construction
Ardeshir Kianercy, Kenneth J. Pienta

8. Microenvironmental Niches and Sanctuaries: A Route to Acquired Resistance
Judith Pérez-Velázquez, Jana L. Gevertz, Aleksandra Karolak, Katarzyna A. Rejniak

9. The Tumor Microenvironment as a Barrier to Cancer Nanotherapy
Louis T. Curtis, Hermann B. Frieboes

10. Microenvironment-Mediated Modeling of Tumor Response to Vascular-Targeting Drugs
Jana L. Gevertz

11. Optimizing Chemotherapeutic Anti-cancer Treatment and the Tumor Microenvironment: An Analysis of Mathematical Models
Urszula Ledzewicz, Heinz Schaettler

12. Progress Towards Computational 3-D Multicellular Systems Biology
Paul Macklin, Hermann B. Frieboes, Jessica L. Sparks, Ahmadreza Ghaffarizadeh, Samuel H. Friedman, Edwin F. Juarez, Edmond Jonckheere, Shannon M. Mumenthaler

Keywords: Biomedicine, Cancer Research, Mathematical and Computational Biology, Biological and Medical Physics, Biophysics