Carrasco, Martin
Modern Proteomics – Sample Preparation, Analysis and Practical Applications
Part I. Sample Preparation Strategies for Proteomics
1. Proteomes, Their Compositions and Their Sources
Anna Kwasnik, Claire Tonry, Angela Mc Ardle, Aisha Qasim Butt, Rosanna Inzitari, Stephen R. Pennington
2. Protein Fractionation and Enrichment Prior to Proteomics Sample Preparation
Andrew J. Alpert
3. Sample Preparation for Mass Spectrometry-Based Proteomics; from Proteomes to Peptides
John C. Rogers, Ryan D. Bomgarden
4. Plant Structure and Specificity – Challenges and Sample Preparation Considerations for Proteomics
Sophie Alvarez, Michael J. Naldrett
5. Improving Proteome Coverage by Reducing Sample Complexity via Chromatography
Uma Kota, Mark L. Stolowitz
Part II. Mass Spectrometry for Proteomics Analysis
6. Database Search Engines: Paradigms, Challenges and Solutions
Kenneth Verheggen, Lennart Martens, Frode S. Berven, Harald Barsnes, Marc Vaudel
7. Mass Analyzers and Mass Spectrometers
Anthony M. Haag
8. Top-Down Mass Spectrometry: Proteomics to Proteoforms
Steven M. Patrie
Part III. Bioinformatic Tools for Proteomics data Analysis and Interpretation
9. Platforms and Pipelines for Proteomics Data Analysis and Management
Marius Cosmin Codrea, Sven Nahnsen
10. Tandem Mass Spectrum Sequencing: An Alternative to Database Search Engines in Shotgun Proteomics
Thilo Muth, Erdmann Rapp, Frode S. Berven, Harald Barsnes, Marc Vaudel
11. Visualization, Inspection and Interpretation of Shotgun Proteomics Identification Results
Ragnhild R. Lereim, Eystein Oveland, Frode S. Berven, Marc Vaudel, Harald Barsnes
12. Protein Inference
Zengyou He, Ting Huang, Can Zhao, Ben Teng
13. Modification Site Localization in Peptides
Robert J. Chalkley
14. Useful Web Resources
Andre Bui, Maria D. Person
15. Mass Spectrometry-Based Protein Quantification
Yun Chen, Fuqiang Wang, Feifei Xu, Ting Yang
16. Bioinformatics Tools for Proteomics Data Interpretation
Karla Grisel Calderón-González, Jesús Hernández-Monge, María Esther Herrera-Aguirre, Juan Pedro Luna-Arias
Part IV. Applications of Proteomics Technologies in Biological and Medical Sciences
17. Identification, Quantification, and Site Localization of Protein Posttranslational Modifications via Mass Spectrometry-Based Proteomics
Mi Ke, Hainan Shen, Linjue Wang, Shusheng Luo, Lin Lin, Jie Yang, Ruijun Tian
18. Protein-Protein Interaction Detection Via Mass Spectrometry-Based Proteomics
Benedetta Turriziani, Alexander Kriegsheim, Stephen R. Pennington
19. Protein Structural Analysis via Mass Spectrometry-Based Proteomics
Antonio Artigues, Owen W. Nadeau, Mary Ashley Rimmer, Maria T. Villar, Xiuxia Du, Aron W. Fenton, Gerald M. Carlson
Part V. Clinical Proteomics
20. Introduction to Clinical Proteomics
John E. Wiktorowicz, Allan R. Brasier
21. Discovery of Candidate Biomarkers
John E. Wiktorowicz, Kizhake V. Soman
22. Statistical Approaches to Candidate Biomarker Panel Selection
Heidi M. Spratt, Hyunsu Ju
23. Qualification and Verification of Protein Biomarker Candidates
Yingxin Zhao, Allan R. Brasier
24. Protocol for Standardizing High-to-Moderate Abundance Protein Biomarker Assessments Through an MRM-with-Standard-Peptides Quantitative Approach
Andrew J. Percy, Juncong Yang, Andrew G. Chambers, Yassene Mohammed, Tasso Miliotis, Christoph H. Borchers
Keywords: Life Sciences, Proteomics, Protein Science, Bioinformatics
- Editor
- Carrasco, Martin
- Mirzaei, Hamid
- Publisher
- Springer
- Publication year
- 2016
- Language
- en
- Edition
- 1
- Series
- Advances in Experimental Medicine and Biology
- Page amount
- 9 pages
- Category
- Natural Sciences
- Format
- Ebook
- eISBN (PDF)
- 9783319414485
- Printed ISBN
- 978-3-319-41446-1