Plasma Cell Dyscrasias

Part I. Monoclonal Gammopathy of Undetermined Significance and Smoldering Myeloma

1. MGUS and Smoldering Multiple Myeloma: Diagnosis and Epidemiology
María-Victoria Mateos, Ola Landgren

Part II. Multiple Myeloma

2. Vision Statement for Multiple Myeloma: Future Directions
Kenneth C. Anderson

3. Genomic Aberrations in Multiple Myeloma
Salomon Manier, Karma Salem, Siobhan V. Glavey, Aldo M. Roccaro, Irene M. Ghobrial

4. Epigenetics in Multiple Myeloma
Siobhan V. Glavey, Salomon Manier, Antonio Sacco, Karma Salem, Yawara Kawano, Juliette Bouyssou, Irene M. Ghobrial, Aldo M. Roccaro

5. Role of Endothelial Cells and Fibroblasts in Multiple Myeloma Angiogenic Switch
Domenico Ribatti, Angelo Vacca

6. Targeting the Bone Marrow Microenvironment
Michele Moschetta, Yawara Kawano, Klaus Podar

7. Multiple Myeloma Minimal Residual Disease
Bruno Paiva, Ramón García-Sanz, Jesús F. San Miguel

8. Treatment of Newly Diagnosed Elderly Multiple Myeloma
Guillemette Fouquet, Francesca Gay, Eileen Boyle, Sara Bringhen, Alessandra Larocca, Thierry Facon, Xavier Leleu, Antonio Palumbo

9. Management of Transplant-Eligible Patients with Newly Diagnosed Multiple Myeloma
Jacob Laubach, Shaji Kumar

10. Treatment of Relapsed/Refractory Multiple Myeloma
Paola Neri, Nizar J. Bahlis, Claudia Paba-Prada, Paul Richardson

11. Treatment of MM: Upcoming Novel Therapies
Sagar Lonial

12. Role of the Immune Response in Disease Progression and Therapy in Multiple Myeloma
Susan J. Lee, Ivan Borrello

13. Transplantation for Multiple Myeloma
Yogesh S. Jethava, Frits Rhee

14. Bone Disease in Multiple Myeloma
Homare Eda, Loredana Santo, G. David Roodman, Noopur Raje

Part III. Primary Amyloidosis, Systemic Light Chain and Heavy Chain Diseases, Plasmacytoma

15. Immunoglobulin Light Chain Systemic Amyloidosis
Angela Dispenzieri, Giampaolo Merlini

Part IV. Waldenstrom’s Macroglobulinemia

16. Waldenstrom Macroglobulinemia: Genomic Aberrations and Treatment
Prashant Kapoor, Stephen M. Ansell, Esteban Braggio

Keywords: Medicine & Public Health, Hematology, Oncology, Molecular Medicine