Trauma Induced Coagulopathy

Part I. Physiology of Hemostasis

1. Cell-Mediated Hemostasis
Maureane Hoffman

2. Thrombin-Antithrombin System
Susan C. Bock

3. Plasmin-Antiplasmin System
Nicola J. Mutch, Nuala A. Booth

Part II. Pathogenesis of Trauma Induced Coagulopathy

4. Thrombin Formation
Shekhar Kumar, Sriram Krishnaswamy

5. Fibrinogen
Eduardo Gonzalez, Ernest E. Moore, Hunter B. Moore

6. Activated Protein C
Benjamin M. Howard, Mitchell Jay Cohen

7. The Endothelium
Pär I. Johansson, Sisse R. Ostrowski

8. Platelets
Scott L. Diamond

9. Fibrinolysis
Hunter B. Moore, Ernest E. Moore, Eduardo Gonzalez

10. Neutrophils, Inflammation, and Innate Immunity in Trauma-Induced Coagulopathy
Christopher D. Barrett, Michael B. Yaffe

11. DAMPs: Damage-Associated Molecular Pattern Molecules in Hemostasis
Charles T. Esmon

12. The Complement System and Coagulation
Narcis I. Popescu, Florea Lupu

13. Disseminated Intravascular Coagulation
Satoshi Gando

Part III. Coagulation Assessment in Trauma Induced Coagulopathy

14. Prothrombin and Partial Thromboplastin Time
Ruchika Goel, Paul M. Ness

15. Fibrinogen Assays
Christoph J. Schlimp, Herbert Schöchl

16. Platelet Aggregometry
Taizo Nakano, Jorge Paola

17. Thrombelastography (TEG®)
Eduardo Gonzalez, Ernest E. Moore, Hunter B. Moore

18. Rotational Thromboelastometry (ROTEM®)
Klaus Görlinger, Daniel Dirkmann, Alexander A. Hanke

Part IV. Management of Trauma Induced Coagulopathy

19. Red Blood Cell Transfusion
F. Bernadette West, Marguerite R. Kelher, Christopher C. Silliman

20. Plasma Transfusion
Ryan A. Lawless, John B. Holcomb

21. Cryoprecipitate Transfusion
Jeannie L. Callum, Bartolomeu Nascimento

22. Platelet Transfusion
Andrew P. Cap, Todd M. Getz, Philip C. Spinella, Heather F. Pidcoke

23. Massive Transfusion Protocols
Alexis M. Moren, Samantha J. Underwood, Martin A. Schreiber

24. Fibrinogen and Clotting Factor Replacement
Massimo Franchini

25. Anti-fibrinolytics
Dominik F. Draxler, Robert L. Medcalf, Russell L. Gruen

Part V. Post-injury Hypercoagulability

26. Venous Thromboembolism
Steven R. Shackford, C. Beth Sise

27. Congenital and Acquired Hypercoagulable States
Joseph Emmerich

Part VI. Organ-Specific Coagulopathy

28. Coagulopathy of Traumatic Brain Injury (TBI)
Marc Maegele

29. Coagulopathy of Liver Disease
Shahzaib Ahmad, Beverley J. Hunt

30. Coagulopathy of Renal Disease
Michael P. Chapman, Anirban Banerjee, Ernest E. Moore

Part VII. Trauma Induced Coagulopathy in Special Populations

31. Pediatrics
Robert I. Parker

32. Pregnancy
T. Marchetti, Philippe Moerloose, A. Casini

33. Management of Chronically Anticoagulated Patients
Jerrold H. Levy

Part VIII. Research of Trauma Induced Coagulopathy

34. Animal Models of Trauma Induced Coagulopathy
Ted Bambakidis, Martin Sillesen, Hasan B. Alam

35. Mathematical Models of Hemostasis
Keith B. Neeves, Karin Leiderman

Keywords: Medicine & Public Health, Traumatic Surgery, Intensive / Critical Care Medicine, General Surgery, Anesthesiology