Targeting Oral Cancer

Part I. The Dynamic Epidemiology of Head and Neck Cancers and Current Treatment Modalities

1. Assessing the Changing Oral and Pharyngeal Cancer Demographic in the United States
Andrew S. Holpuch, Susan R. Mallery

2. The Emerging Role of HPV in Head and Neck Cancer
Thomas E. Carey

3. Oral Cancer: Location, Staging, Surgical Management, and Outcomes
Michael Z. Chen, Robert H. Mathog, Andrew M. Fribley, George H. Yoo

4. Chemotherapy in Head and Neck Squamous Cell Cancer
Daniela M. Burchhardt, Ammar Sukari

Part II. HNSCC: Molecular Progression, Biomarkers and Stem Cells

5. Molecular Signaling in Oral Cancer Invasion and Metastasis
Insoon Chang, Aasia O. Rehman, Cun-Yu Wang

6. Cancer Stem Cells in the Biology and Treatment of Head and Neck Squamous Cell Carcinoma
Hong S. Kim, April Adams, Jacques E. Nör

7. HNSCC Biomarkers Derived from Key Processes of Cancerogenesis
Martina Raudenska, Jaromir Gumulec, Andrew M. Fribley, Michal Masarik

Part III. Current Trends in Head and Neck Cancer Treatment and Novel Therapeutic Approaches

8. Emerging Molecular Targets in the Treatment of Head and Neck Squamous Cell Carcinoma
Blake M. Warner, Jennifer Grandis

9. Immunotherapy in Head and Neck Cancers
Zipei Feng, Carlo B. Bifulco, Rom Leidner, R. Bryan Bell, Bernard A. Fox

10. The Unfolded Protein Response as a Therapeutic Target for Head and Neck Squamous Cell Carcinoma
Danielle M. Garshott, Shelby A. Bechler, Daniela M. Burchhardt, Priyanka Shah O’Brien, George H. Yoo, Daniel J. Chiego, Aasia O. Rehman, Michael U. Callaghan, Andrew M. Fribley

11. Targeting Coagulation Mediators in Head and Neck Cancer
Rohith Jesudas, Qinghua Zeng, Danielle M. Garshott, Nicholas Yoo, Andrew M. Fribley, Jordan A. Shavit, Michael U. Callaghan

12. Mucosal Therapy for Potentially Malignant Diseases and OSCC
Peter F. Svider, Blake M. Warner, Scott J. Schwartz, Danielle M. Garshott, James D. Weinstein, Andrew M. Fribley

Keywords: Dentistry, Dentistry, Oncology, Oral and Maxillofacial Surgery