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Hughes, Claude L.

Translational Toxicology

Hughes, Claude L. - Translational Toxicology, ebook

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ISBN: 9783319274492
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Table of contents

Part I. Introduction

1. The Opportunity to Translate Developmental Toxicology into a Therapeutic Discipline
Claude L. Hughes, Michael D. Waters, David Allen, Iyabo Obasanjo

2. The Role of Toxicokinetics and Toxicodynamics in Developmental and Translational Toxicology
Edward L. Croom

Part II. Toxicant Modes of Action and Biomarkers

3. Mutational Effects
Edward L. Croom

4. Ligand-Mediated Toxicology: Characterization and Translational Prospects
Rais Ansari, Claude L. Hughes, Kazim Husain

5. Effects of Environmentally Acquired Heavy Metals and Nutrients on the Epigenome and Phenotype
David A. Skaar, Susan K. Murphy, Cathrine Hoyo

6. Fetal Imaging and Effects of Exposures on Growth and Function
Elena Demicheva, Fatima Crispi

Part III. Developmental Risks of Exposures and Potential Translational Toxicology Therapeutics

7. Ovarian Toxicity of Environmental Contaminants: 50 Shades of Grey
M. A. Dominguez, J. C. Sadeu, M. T. Guerra, H. C. Furlong, Sharnjit Baines, Warren G. Foster

8. The “Toxic” Effects of a Perinatal Obesogenic Environment: Maternal Obesity and Impacts on Future Generations
Leon Chalil, Deborah M. Sloboda

9. The Role of Environmental Exposures in Preterm Birth
Kelly K. Ferguson, John D. Meeker

10. The Impact of Environmental Stressors on DNA Methylation, Neurobehavioral Development, and Chronic Physical Aggression: Prospects for Early Protective Interventions
Richard E. Tremblay, Linda Booij, Nadine Provençal, Moshe Szyf

11. Coffee Health Effects from Early Fetal Development Through Childhood and Adolescence
Roseane Maria M. Santos, Darcy Roberto A. Lima

12. Ethical Considerations in Development of Future Therapies for Women and Children
Toby Schonfeld

Keywords: Biomedicine, Pharmacology/Toxicology, Environmental Health

Editor
 
Publisher
Springer
Publication year
2016
Language
en
Edition
1st ed. 2016
Series
Molecular and Integrative Toxicology
Category
Medicine, Health Care, Mode
Format
Ebook
eISBN (PDF)
9783319274492
Printed ISBN
978-3-319-27447-8

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