Sickle Cell Anemia

1. Hemoglobin: Structure, Synthesis and Oxygen Transport
Susan E. Jorge, Daniela M. Ribeiro, Magnun N. N. Santos, Maria Fátima Sonati

2. Sickle Cell Anemia: History and Epidemiology
Frédéric B. Piel, Thomas N. Williams

3. Overview of Sickle Cell Anemia Pathophysiology
Martin H. Steinberg

4. Red Blood Cells and the Vaso-Occlusive Process
Nancy J. Wandersee, Cheryl A. Hillery

5. Leukocytes in the Vaso-Occlusive Process
Dachuan Zhang, Paul S. Frenette

6. Hypercoagulability and Sickle Cell Disease
Marina Pereira Colella, Erich Vinicius Paula, Margareth Castro Ozelo, Fabiola Traina

7. Cardiovascular Adaptations to Anemia and the Vascular Endothelium in Sickle Cell Disease Pathophysiology
Lydia H. Pecker, Hans C. Ackerman

8. Inflammation and Sickle Cell Anemia
Camila Bononi Almeida, Gregory J. Kato, Nicola Conran

9. Clinical Manifestations of Sickle Cell Anemia: Infants and Children
Robert Sheppard Nickel, Lewis L. Hsu

10. Treatment of Childhood Sickle Cell Disease
Rouba Abdennour, Miguel R. Abboud

11. Priapism in Sickle Cell Disease: New Aspects of Pathophysiology
Mário A. Claudino, Carla F. Franco Penteado, Kleber Yotsumoto Fertrin

12. Clinical Manifestations and Treatment of Adult Sickle Cell Disease
Fernando Ferreira Costa, Kleber Yotsumoto Fertrin

13. Hemoglobin Sβ Thalassemia, SC Disease and SD Disease: Clinical and Laboratorial Aspects
Sara T. Olalla Saad, Simone O. Gilli

14. Sickle Cell Disease in Africa and the Arabian Peninsula: Current Management and Challenges
Adekunle Adekile, Julie Makani

15. Genetic Factors Modifying Sickle Cell Disease Severity
Kate Gardner, Swee Lay Thein

16. Future Perspectives for the Treatment of Sickle Cell Anemia
Kerri Nottage, Jeremie Estepp, Jane Hankins

Keywords: Medicine & Public Health, Hematology, Internal Medicine, Medical Biochemistry, Medicine/Public Health, general