Pavelka, Margit

Functional Ultrastructure

Pavelka, Margit - Functional Ultrastructure, ebook


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ISBN: 9783211263921
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Table of contents

1. Structural Organisation of a Mammalian Cell

2. Architecture of the Cell Nucleus

3. Cytochemical Detection of Ribonucleoproteins

4. Nuclear Lamina

5. Detection of Sites of DNA Replication and of Interphase Chromosome Domains

6. Nucleolus

7. Changes of the Nucleolar Architecture

8. Detection of Sites of RNA Synthesis

9. Nuclear Pore Complexes

10. Nuclear Pore Complexes: Structural Changes as Monitored by Time-Lapse Atomic Force Microscopy

11. Mitosis and Cell Division

12. Apoptosis

13. Viral Inclusions

14. Secretory Pathway of Pancreatic Acinar Cells

15. Ribosomes, Rough Endoplasmic Reticulum

16. Nuclear Envelope and Rough Endoplasmic Reticulum

17. Rough Endoplasmic Reticulum: Site of Protein Translocation and Initiation of Protein N-Glycosylation

18. Oligosaccharide Trimming, Reglucosylation, and Protein Quality Control in the Rough Endoplasmic Reticulum

19. Rough Endoplasmic Reticulum: Storage Site of Aggregates of Misfolded Glycoproteins

20. Russell Bodies and Aggresomes Represent Different Types of Protein Inclusion Bodies

21. Smooth Endoplasmic Reticulum

22. Proliferation of the Smooth Endoplasmic Reticulum

23. Pre-Golgi Intermediates

24. Pre-Golgi Intermediates: Oligosaccharide Trimming and Protein Quality Control

25. Golgi Apparatus: A Main Crossroads Along Secretory Pathways

26. Protein Secretion Visualised by Immunoelectron Microscopy

27. Protein N-Glycosylation: Oligosaccharide Trimming in the Golgi Apparatus and Pre-Golgi Intermediates

28. Golgi Apparatus: Site of Maturation of Asparagine-Linked Oligosaccharides

29. Cell-Type-Related Variations in the Topography of Golgi Apparatus Glycosylation Reactions

30. Cell-Type-Related Differences in Oligosaccharide Structure

31. Topography of Biosynthesis of Serine/Threonine-Linked Oligosaccharides

32. Golgi Apparatus and TGN — Secretion and Endocytosis

33. Golgi Apparatus, TGN and trans-Golgi-ER

34. Golgi Apparatus, TGN and trans-Golgi-ER: Tilt Series

35. Brefeldin A-Induced Disassembly of the Golgi Apparatus

36. Brefeldin A-Treatment: Tubulation of Golgi Apparatus and Endosomes

37. Brefeldin A-Treatment: Effect on Retrograde Transport of Internalised WGA

38. Brefeldin A-Treatment: Transitional ER-Elements and Pre-Golgi Intermediates

39. Heat Shock Response of the Golgi Apparatus

40. Changes of the Golgi Apparatus Upon ATP-Depletion and ATP-Replenishment

41. Secretory Granules

42. Secretory Granule Types

43. Receptor-Mediated Endocytosis Via Clathrin-Coated Vesicles and Virus Internalisation

44. Endosomes and Endocytic Pathways

45. Endocytic Trans-Golgi Network and Retrograde Traffic into the Golgi Apparatus

46. Tubular Pericentriolar Endosomes

47. Langerhans Cells and Birbeck Granules: Antigen Presenting Dendritic Cells of the Epidermis

48. Caveolae

49. Fluid-Phase Endocytosis and Phagocytosis

50. Lysosomes

51. Lysosomes: Localisation of Acid Phosphatase, Lamp and Polylactosamin

52. I-Cell Disease

53. Gaucher’s Disease

54. Fabry’s Disease

55. GM2 Gangliosidoses

56. Farber’s Disease

57. Wolman’s Disease

58. Glycogenosis Type II

59. Cystinosis

60. Autophagosomes: Organelles for Limited Self-Digestion

61. Mitochondria: Crista and Tubulus-Types

62. Abnormalities of Mitochondria

63. Peroxisomes: Multitalented Organelles

64. Peroxisome Biogenesis

65. Peroxisomes: Adaptive Changes

66. Peroxisomal Diseases

67. Glycogen

68. Glycogenosis Type I

69. Erythropoietic Protoporphyria

70. Cytocentre, Centrosome, and Microtubules

71. Effects of Microtubule Disruption

72. Actin Filaments

73. Intermediate Filaments

74. Mallory Bodies

75. The Plasma Membrane

76. Cells in Culture

77. Brush Cell

78. Glycocalyx (Cell Coat)

79. Glycocalyx: Cell Type Specificity and Domains

80. Glycocalyx Changes in Tumours

81. Junctional Complex

82. Tight Junctions and Gap Junctions

83. Spot Desmosomes

84. Cellular Interdigitations

85. Basal Labyrinth

86. Basement Membrane

87. Glomerular Basement Membrane

88. Alport’s Syndrome (Hereditary Nephritis)

89. Descemet’s Membrane

90. Skin Basement Membrane and Keratinocyte Hemidesmosomes: An Epithel-Connective Tissue Junctional Complex

91. Epidermolysis Bullosa Simplex

92. Pancreatic Acinus

93. Acinar Centre: Acinar and Centroacinar Cells

94. Pancreatic Intercalated Duct

95. Submandibular Gland

96. Parietal Cells of Stomach: Secretion of Acid

97. Intercalated Cells of Kidney: Important Regulators of Acid-Base Balance

98. Endocrine Secretion: Insulin-Producing Beta Cells of Islets of Langerhans

99. Impaired Insulin Processing in Human Insulinoma

100. Cells of the Disseminated Endocrine System

101. Liver Epithelium

102. Liver Epithelium: Bile Canaliculi

103. Liver Epithelium: Pathway of Secretory Lipoprotein Particles

104. Choroid Plexus Ependyma

105. Small Intestine: Absorptive Cells

106. Small Intestine: Pathway of Lipids

107. Renal Proximal Tubule: A Reabsorption Plant

108. Parathyroid Hormone Response of Renal Proximal Tubules

109. Photoreceptor Cells of the Retina: Signalling of Light

110. Photoreceptor Cells of the Retina: Light-Induced Apoptosis

111. Corneal Epithelium

112. Epidermis

113. Differentiation of Keratinocytes and Formation of the Epidermal Fluid Barrier

114. The Tracheo-Bronchial Epithelium

115. Ciliary Pathology: Immotile Cilia Syndrome and Kartagener Syndrome

116. Alveoli: Gas Exchange and Host Defense

117. Umbrella Cell — Surface Specialisations

118. Umbrella Cell — Fusiform Vesicles

119. Continuous Capillary, Weibel-Palade Bodies

120. Fenestrated Capillary

121. Endothelio-Pericyte and Endothelio-Smooth Muscle Cell Interactions

122. Glomerulus: A Specialised Device for Filtering

123. Pathology of the Glomerular Filter: Minimal Change Glomerulopathy and Congenital Nephrotic Syndromes

124. Pathology of the Glomerulus: Membranous Glomerulonephritis

125. Pathology of the Glomerulus: Membranoproliferative Glomerulonephritis

126. Pathology of the Glomerulus: Chronic Allograft Glomerulopathy

127. Loose Connective Tissue

128. Fibroblast, Fibrocyte, Macrophage

129. Collagen and Elastic Fibres

130. Eosinophilic Granulocyte, Plasma Cell, Macrophage, Mast Cell

131. Dense Connective Tissue: Collagen Bundles in the Cornea

132. Bowman’s Layer

133. Amyloidosis of Kidney

134. Amyloid Fibrils: Growth as Seen by Time Lapse, Atomic Force Microscopy

135. Articular Cartilage

136. Osteoblasts and Osteocytes

137. Osteoclast

138. Myofibrils and Sarcomere

139. Sarcoplasmic Reticulum, Triad, Satellite Cell

140. Neuromuscular Junction

141. Muscular Dystrophies

142. Myofibrils, Intercalated Disk

143. Smooth Muscle Cells, Synapse Á Distance


145. Central Nervous System: Neuron, Glial Cells

146. Blood-Brain Barrier, Synapses

147. Unmyelinated Nerve Fibre

148. Peripheral Nerve: Connective Tissue Components

149. Myelinated Nerve Fibre, Myelin

150. Node of Ranvier

151. Axonal Degeneration

152. Neuroaxonal Dystrophy

153. Neuropathies Associated with Dysproteinaemias

154. Metachromatic Leukodystrophy

155. Neuronal Ceroid Lipofuscinosis

156. Red Blood Cells and cells of the Erythroid Lineage

157. Neutrophilic Granulocyte

158. Eosinophilic Granulocyte

159. Monocyte

160. Lymphocyte

161. Megakaryocyte and Thrombocyte

162. Thrombocytes

Keywords: Biomedicine, Medical Microbiology, Molecular Medicine, Medical Biochemistry, Pathology

Publication year
Page amount
342 pages
Medicine, Health Care, Mode

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