Targeted Therapies

1. Resistance to Targeted Therapies As a Result of Mutation(s) in the Target
Alexis B. Cortot, Pasi A. Jänne

2. The Dynamics of the Cell Signaling Network; Implications for Targeted Therapies
Daniel Gioeli

3. Cancer Signaling Network Analysis by Quantitative Mass Spectrometry
Jason R. Neil, Forest M. White

4. Development and Implementation of Array Technologies for Proteomics: Clinical Implications and Applications
Julia D. Wulfkuhle, Menawar Khalil, Joseph C. Watson, Lance A. Liotta, Emanuel F. Petricoin

5. Using Phosphoflow™ to Study Signaling Events of Subpopulations Resistant to Current Therapies
Omar D. Perez

6. Mathematical and Computational Models in Cancer
Sudhir Chowbina, Kevin A. Janes, Shayn M. Peirce, Jason A. Papin

7. Somatic Evolution of Acquired Drug Resistance in Cancer
John W. Pepper

8. Interrogating Resistance to Targeted Therapy Using Genetically Engineered Mouse Models of Cancer
Edward Gunther

9. microRNA: A Potential Therapy Able to Target Multiple Cancer Pathways
Benjamin Kefas, Benjamin W. Purow

10. Rational Combination of Targeted Agents to Overcome Cancer Cell Resistance
Yun Dai, Steven Grant

Keywords: Medicine & Public Health, Oncology, Molecular Medicine, Cancer Research