Autism

Part I.Molecular and Clinical Genetics

1. Engrailed2 and Cerebellar Development in the Pathogenesis of Autism Spectrum Disorders
Ian T. Rossman, Emanuel DiCicco-Bloom

2. Teratogenic Alleles in Autism and Other Neurodevelopmental Disorders
William G. Johnson, Madhura Sreenath, Steven Buyske, Edward S. Stenroos

3. Cholesterol Deficit in Autism: Insights from Smith–Lemli–Opitz Syndrome
Alka Aneja, Elaine Tierney

4. Autism in Genetic Intellectual Disability
Walter E. Kaufmann, George T. Capone, Megan Clarke, Dejan B. Budimirovic

Part II.Neurotransmitters and Cell Signaling

5. Serotonin Dysfunction in Autism
Mary E. Blue, Michael V. Johnston, Carolyn B. Moloney, Christine F. Hohmann

6. Excitotoxicity in Autism
Martin Evers, Eric Hollander

7. Prenatal ß2-Adrenergic Receptor Signaling and Autism:
Susan L. Connors

Part III.Endocrinology, Growth, and Metabolism

8. A Role for Fetal Testosterone in Human Sex Differences
Bonnie Auyeung, Simon Baron-Cohen

9. Interaction between Genetic Vulnerability and Neurosteroids in Purkinje cells as a Possible Neurobiological Mechanism in Autism Spectrum Disorders
Flavio Keller, Roger Panteri, Filippo Biamonte

10. Insulin-Like Growth Factors
Raili Riikonen

11. Oxidative Stress and the Metabolic Pathology of Autism
S. Jill James

Part IV.Immunology, Maternal-Fetal Interaction, and Neuroinflammation

12. The Immune System in Autism
Luke Heuer, Paul Ashwood, Judy Water

13. Maternal Immune Activation, Cytokines and Autism
Paul H. Patterson, Wensi Xu, Stephen E.P. Smith, Benjamin E. Devarman

14. Maternal Antibodies and the Placental–Fetal IgG Transfer Theory
Christina M. Morris, Mikhail Pletnikov, Andrew W. Zimmerman, Harvey S. Singer

15. Can Neuroinflammation Influence the Development of Autism Spectrum Disorders?
Carlos A. Pardo-Villamizar

Part v.Neuroanatomy and Neural networks

16. The Significance of Minicolumnar Size Variability in Autism
Manuel F. Casanova

17. Imaging Evidence for Pathological Brain Development in Autism Spectrum Disorders
Stephen R. Dager, Seth D. Friedman, Helen Petropoulos, Dennis W.W. Shaw

18. Information Processing, Neural Connectivity, and Neuronal Organization
Nancy J. Minshew, Diane L. Williams, Kathryn McFadden

Part VI.Environmental Mechanisms and Models

19. Evidence for Environmental Susceptibility in Autism
Isaac N. Pessah, Pamela J. Lein

20. An Expanding Spectrum of Autism Models
Martha R. Herbert, Matthew P. Anderson

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Keywords: MEDICAL / Public Health MED078000