Animal Models of Acute Neurological Injuries

I. Animal Care and Surgery

1. Animal Protocol
Laurel D. Schantz

2. Anesthesia and Analgesia for Research Animals
Andrew R. Blickman, Lisa J. Brossia

3. Rodent Surgical Procedures and Tissue Collection
Robert Ayer, Julian Cahill, Takashi Sugawara, Vikram Jadhav, John H. Zhang

4. Brain Monitoring
Julian Cahill, John H. Zhang

5. Veterinary Care Methods for Rats and Mice in Experimental Spinal Cord Injury Studies
Aaron H. Puckett, Christine D. Nunn, Stephen M. Onifer

II. Cerebral Ischemic Animal Models

6. Four-Vessel Occlusion Model in Rats
Ping Deng, Zao C. Xu

7. Rat Model of Global Cerebral Ischemia: The Two-Vessel Occlusion (2VO) Model of Forebrain Ischemia
Ami P. Raval, Chunli Liu, Bingren R. Hu

8. Asphyxial Cardiac Arrest
Clifton W. Callaway, Eric S. Logue

9. Rodent Model of Pediatric Asphyxial Cardiac Arrest
Mioara D. Manole, Robert W. Hickey, Henry L. Alexander, Robert S.B. Clark

10. Transient Global Cerebral Ischemia Model in Mice
Kuniyasu Niizuma, Hidenori Endo, Chikako Nito, D. Jeannie Myer, Gab Seok Kim, Teiji Tominaga, Pak H. Chan

11. Transient Middle Cerebral Artery Occlusion Model in Rodents
Ying Mao, Wei Zhu, Guo-Yuan Yang

12. Three-Vessel Middle Cerebral Artery Occlusion Model
T. N. Lin, S. T. Chen, Y. Y. He, W. M. Cheung, C. Y. Hsu

13. A Thromboembolic Rat Model of Focal Cerebral Ischemia and Reperfusion with tPA
Yoshihiro Murata, Xiaoying Wang, Eng H. Lo

14. Targeted Occlusion to Surface and Deep Vessels in Neocortex via Linear and Nonlinear Optical Absorption
David Kleinfeld, Beth Friedman, Patrick D. Lyden, Andy Y. Shih

15. Middle Cerebral Artery Occlusion Suture Model for Mice
Feng Zhang, Steven H. Graham, Jun Chen

16. Intraluminal Middle Cerebral Artery Occlusion Model in Mice
Masaya Oda, Taku Sugawara, Kohei Kokubun, Kazuo Mizoi, Hiroyuki Kinouchi

17. Cerebral Hypoxia—Ischemia Model in Adult Mice
Faisal Adhami, Chia-Yi Kuan

18. Cerebral Hypoxia—Ischemia in Neonatal Rats or Mice: A Model of Perinatal Brain Injury
Changlian Zhu, Xiaoyang Wang, Klas Blomgren

19. Cerebral Palsy Model of Uterine Ischemia in Pregnant Rabbits
X. Ji, M. Derrick, S. Tan

20. Model of Neonatal Focal Cerebral Ischemia-Reperfusion
Zinaida S. Vexler, Donna M. Ferriero

III. Cerebral Hemorrhage Animal Models

21. Monofilament Perforation Subarachnoid Hemorrhage Rat Model
Julian Cahill, John H. Zhang

22. Blood Injection Subarachnoid Hemorrhage Rat Model
Hartmut Vatter, Erdem Gueresir, Volker Seifert

23. Filament Perforation Subarachnoid Hemorrhage: Mouse Model
Hideyuki Kamii, Teiji Tominaga

24. Blood Injection Subarachnoid Hemorrhage Mouse Model
Tarkan Calisaneller, Chih-Lung Lin, Naoya Ukita, Ryo Yoshimura, Yi Wang, Mark Fitzgerald, Kevin S. Lee

25. Blood Injection Cerebral Vasospasm Rabbit Model
Mario Zuccarello

26. Double Blood-Injection Cerebral Vasospasm Canine Model
Shigeru Nishizawa

27. Nonhuman Primate Blood-Clot Placement Cerebral Vasospasm Model
Ayako Kawashima, R. Loch Macdonald

28. Blood Injection Intracerebral Hemorrhage Rat Model
Thomas O'Lynnger, Ya Hua, Guohua Xi

29. Bacterial Collagenase Injection Intracerebral Hemorrhage Rat Model
Mark Grossetete, Gary A. Rosenberg

30. Blood Injection Intracerebral Hemorrhage Mouse Model
Ludmila Belayev

31. Blood Injection Intracerebral Hemorrhage Pig Model
Ya Hua, Yuxiang Gu, Guohua Xi

IV. Traumatic CNS Injury Animal Models

32. Fluid Percussion Injury Model
Jonathan Lifshitz

33. Controlled Cortical Impact Injury Model
C. Edward Dixon, Anthony E. Kline

34. Marmarou Weight Drop Injury Model
Christina R. Marmarou, Ruth Prieto, Keisuke Taya, Harold F. Young, Anthony Marmarou

35. MASCIS Spinal Cord Contusion Model
Wise Young

36. Infinite Horizon Spinal Cord Contusion Model
Stephen Scheff, Kelly N. Roberts

37. The Ohio State University ESCID Spinal Cord Contusion Model
Lyn B. Jakeman, Dana M. McTigue, Patricia Walters, Bradford T. Stokes

38. Acute Clip Impact-Compression Model
Charles H. Tator, Peter Poon

39. Experimental Laceration Spinal Cord Injury Model
Yi Ping Zhang, Lisa B.E. Shields, Christopher B. Shields

40. Rodent Spinal Cord Demyelination Models
Sarah C. Jernigan, Yi Ping Zhang, Christopher B. Shields, Scott R. Whittemore

41. Spinal Cord Lateral Hemisection and Implantation of Guidance Channels
Xiaofei Wang, Xiao-Ming Xu

42. Spinal Root Avulsion and Repair Model
Tak-Ho Chu, Wutian Wu

Keywords: Biomedicine, Neurosciences, Neurology, Animal Models