Leong, Stanley P. L.

From Local Invasion to Metastatic Cancer

Leong, Stanley P. L. - From Local Invasion to Metastatic Cancer, ebook


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ISBN: 9781603270878
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Table of contents

2. Frontiers of Cancer Research: The Metastasis Challenge
Simone John, Christina H. Stuelten, John E. Niederhuber

1. Part I. Innovation and Experience

3. Vascular Endothelial Growth Factor: Basic Biology and Clinical Applications
Napoleone Ferrara

4. Proliferation and Cancer Metastasis from the Clinical Point of View
Blake Cady

5. Gastrointestinal Cancer and the Lymphatic System: Patterns of Micrometastasis and Lymphatic Mapping with Clinical Outcome
Takashi Aikou, Yuko Kitagawa, Yoshikazu Uenosono, Shoji Natsugoe, Anton J. Bilchik, Naoto T. Ueno

6. Redefined Lymphatic Anatomy of the Breast with Clinical Implications
Hiroo Suami, Wei-Ren Pan, G. Ian Taylor

7. Should Axillary Lymph Node Dissection be Done for Breast Cancer?
Douglas Reintgen, Blake Cady, Stanley P.L. Leong

2. Part II. Tumor Microenvironment and Proliferation

8. Overview of Tumor Cells and the Microenvironment
Richard E.B. Seftor, Elisabeth A. Seftor, Lynne-Marie Postovit, Mary J.C. Hendrix

3. Part III. Lymphangiogenesis and Angiogenesis

9. Heme/Lymphvasculogenesis, Hem/Lymphangiogenesis, Hem/Lymphangiotumorigenesis, and Tumor Hem/Lymphangiogenesis: Need for a Terminology Adjustment
Marlys H. Witte, Michael Dellinger, Michael J. Bernas, Charles L. Witte

10. Tumor Lymphangiogenesis: What We Know and Don't Know
Antje Neeb, Jonathan P. Sleeman

4. Part IV. Diagnostic Imaging of Cancer

11. Molecular Imaging of Cancer: Receptors, Angiogenesis, and Gene Expression
Heiko Schöder

12. MRI and Ultrasound Imaging of Lymph Nodes
Marika Decyk, Yuko Kono, Robert Mattrey

13. Molecular Imaging of the Sentinel Lymph Node via Lymphoseek
Antonia Woehnl, Carl K. Hoh, Jeanette Méndez, Denise D. Darrah, Richard C. Orahood, David R. Vera, Anne M. Wallace

14. Lymphatic Disorders in Patients with Cancer
Edwin C. Glass, Emily Iker

15. 3D-CT Lymphography for Mapping Metastatic Breast Sentinel Node and Axillary Nodes
Koji Yamashita, Kazuo Shimizu

16. Molecular Imaging of Neuroendocrine Cancer by Fusion SPET/CT
Jean L. Alberini, Myriam Wartski, Veronique Edeline, Olivier Madar, Soraya Banayan, Dominique Bellet, Alain P. Pecking

17. Functional Molecular Imaging of Prostate Cancer Lymph Node Metastases: Adenovirus-Mediated Lymph Node Detection
Saul J. Priceman, Jeremy B. Burton, Lily Wu

5. Part V. Therapeutic Targeting of the Lymphovascular System

18. Therapeutic Targeting of the Lymphovascular System in Cancer: Promise and Challenge
Bronislaw Pytowski, Jeffrey E. Gershenwald

19. Comparison of Liposomal and Aqueous Blue Dye in Visualization of Lymph Nodes Prior to Lymphadenectomy
Peter Hirnle

6. Part VI: Molecular Mechanisms of Metastasis

20. The Role of Lymphangiogenesis in Regional Lymph Node Metastasis: Animal Models
S. David Nathanson, Cathie G. Miller, James H. Paxton

21. Sentinel Lymph Node Chemokine Microenvironment Modulated by Melanoma Metastasis
Minoru Kitago, Steve R. Martinez, Takuji Mori, Kazuo Koyanagi, Naoyuki Umetani, Roderick R. Turner, Dave S.B.Hoon

22. Circulating and Disseminated Tumor Cells from Solid Tumors—Research and Clinical Aspects
Catherine Alix-Panabières, Hope S. Rugo, John W. Park, Klaus Pantel

23. Head and Neck Cancer: An Example for the Role of Chemokine Receptors in Tumor Progression and Metastasis
Anja Muller, Bernhard Homey, Robert L. Ferris

24. Tumor and Lymph Node Lymphangiogenesis
Michael Detmar

25. Treg, Chemokines, and Other Small Molecules: Role in Metastasis and Its Prevention
Darryl A. Oble, F. Stephen Hodi, Gregory Y. Lauwers, Glenn Dranoff, Martin C. Mihm

7. Part VII: Molecular Targeted Therapy Against Growth Factor Receptors,

26. Molecular Targeting of Lymphangiogenesis and Tumor Metastasis
Caroline A. Heckman, Tanja Holopainen, Kari Alitalo

27. Combined Targeting of EGFR and Angiogenesis in Aerodigestive Carcinomas
Michalis V. Karamouzis, Athanassios Argiris

28. Targeting Signaling Pathways in Cancer Therapy
David Berz, Elise McCormack, Anthony Mega, Harold J. Wanebo

8. Part VIII: Impact of Nodal Status and Tumor Burden in Sentinel Nodes on the

29. Micrometastasis of Melanoma to Sentinel Lymph Nodes
Stanley P.L. Leong

30. Sentinel Lymph Node Micrometastases in Breast Cancer: Prognostic Relevance and Therapeutic Implications
Igor Langer, Ulrich Guller, Carsten Thomas Viehl, Markus Zuber

31. Micrometastasis of Genitourinary Cancer to Sentinel Lymph Nodes
Ramon Cabanas

32. Sentinel Lymph Node Mapping in Colorectal Cancer
Sukamal Saha, Saad Sirop, Mehul Soni, Douglas Iddings, David Wiese, Anton J Bilchik, Thomas Beutler, Maher Ghanem, Kiet A Doan, Carsten Thomas Viehl, Markus Zuber

33. Application of Cancer Biology in Cancer Staging and Predicting Clinical Outcome
Frederick L. Greene

9. Part IX: Immune Responses in the Draining Lymph Nodes Against Cancer:

34. Role of Lymph Nodes in Immunotherapy of Malignant Tumors
Walter T. Lee, Suyu Shu

35. Tumor-Related Immune Modulation of the Regional Lymph Nodes
Rong Rong Huang, Eijun Itakura, Duan-Ren Wen, Alistair J. Cochran

36. Reversal of Immune Suppression in Sentinel Lymph Nodes
Richard Essner

37. Vaccine-Primed Lymph Node Cells in the Adoptive Immunotherapy of Cancer: Presence of Host Immune Suppression Induced by Established Cancer
Shuang Wei, Andrew B. Shreiner, Alfred E. Chang

10. Part X: The Role of Stem Cells in Cancer Metastasis

38. Cancer Stem Cells in Metastatic Melanoma
Jim B. Boonyaratanakornkit, Janellen E. Smith, Ruby Ghadially

39. Implications of Cancer Stem Cells for Tumor Metastasis
Maziyar A. Kalani, Piero Dalerba, Michael F. Clarke

40. Prostate Cancer Stem Cells and Their Involvement in Metastasis
Hangwen Li, Dean G. Tang

11. Part XI: Genomic Signatures of Cancer: Basis for Selective Adjuvant

41. Estrogen Receptor-Positive Breast Cancer: Traditional Prognostics, Molecular Pathology: A New Breast Cancer Taxonomy and 21st Century Personalized Prognostic and Predictive Assays
Frederick L. Baehner

42. Molecular Signatures in Melanoma Progression
Suraj S. Venna, Mohammed Kashani-Sabet

12. Part XII: Promising New Treatments for Solid Tumors

43. Targeted Therapy for Breast Cancer: A Focus on HER2/neu and Antiangiogenic Therapy
Hope S. Rugo, Amy Ying-Ju Lin

44. Advances in the Treatment of Colorectal Cancer: Targeting Receptors of Disease
Wen Wee Ma, Antonio Jimeno, Michael A. Choti

45. Developments in the Management of Genitourinary Malignancies: Prostate Cancer and Renal Cell Carcinoma
Charles J Ryan

46. Advances in the Treatment of Lung Cancer
Juliana Karrim, Sarita Dubey

13. Part XIII: Recent Advances in the Treatment of Melanoma

47. Pegylated Interferons in the Adjuvant Treatment of Melanoma
Dirk Schadendorf

48. Sorafenib, a Multikinase Inhibitor: Results from Clinical Trials in Melanoma Patients
Axel Hauschild, Katharina C. Kähler, Friederike Egberts

49. Targeting Immunological Synapse: New Horizons in Immunotherapy for Cancer
Bartosz Chmielowski, Antoni Ribas

50. Cutaneous Metastases of Melanoma: New Treatment Options
Claus Garbe, Benjamin Weide, Annette Pflugfelder, Thomas Eigentler

51. Neoadjuvant Approaches in Melanoma
Ahmad A. Tarhini, John M. Kirkwood

52. Implications of Chemo/Biochemotherapy in the Treatment of Metastatic Melanoma
Sanjiv S. Agarwala

14. Part XIV: Future Perspectives

53. Future Perspectives for Cancer Metastasis: Unanswered Questions and Unquestioned Answers
Stanley P.L. Leong, Marlys H. Witte

Keywords: Medicine & Public Health, Oncology, Surgical Oncology, Radiotherapy, Pathology

Publication year
Current Clinical Oncology
Page amount
25 pages
Medicine, Health Care, Mode

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