Myeloma Therapy

I. Biologic Consideration and Myeloma

1. Staging in Multiple Myeloma
Leonard T. Heffner

2. Epidemiology of Multiple Myeloma
Amelia A. Langston, Dixil Francis

3. Basic Biology of Plasma Cell Dyscrasias: Focus on the Role of the Tumor Microenviroment
Marc S. Raab, Kenneth C. Anderson

4. Biology-Based Classification and Staging of Multiple Myeloma
Wee Joo Chng, Peter Leif Bergsagel

5. Cytogenetic Abnormalities in Multiple Myeloma: The Importance of FISH and Cytogenetics
Esteban Braggio, Michael Sebag, Rafael Fonseca

II. Historical and Cytotoxic Agent-Based Therapies for Myeloma

6. Role of Autologous Stem Cell Transplantation in Multiple Myeloma
Jean-Luc Harousseau

7. Maintenance Therapy in Multiple Myeloma
Jonathan L. Kaufman, Ronald Mihelic, Sagar Lonial

8. Therapy for Patients not Eligible for Autologous Transplant
Bringhen Sara, Palumbo Antonio

9. Current Role of Anthracyclines in the Treatment of Multiple Myeloma
Sikander Ailawadhi, Asher Chanan-Khan

III. Immune-Based Therapies

10. Allogeneic Transplantation for Multiple Myeloma
Fengrong Wang, Edmund K. Waller

11. Immunobiology and Immunotherapy of Multiple Myeloma
Madhav V. Dhodapkar

12. Antibody and Other Immune-Based Therapies for Myeloma
Nikhil C. Munshi, Yu-Tzu Tai

IV. Existing Novel Agents

13. Thalidomide in Patients with Relapsed Multiple Myeloma
Ashraf Badros

14. Thalidomide: Induction Therapy
Francis K. Buadi, S. Vincent Rajkumar

15. The Role of Bortezomib in the Treatment of Relapsed and Refractory Multiple Myeloma
Paul G. Richardson, Constantine S. Mitsiades, Robert Schlossman, Teru Hideshima, Irene Ghobrial, Nikhil C. Munshi, Kenneth C. Anderson

16. Bortezomib as Induction Therapy in Patients with Multiple Myeloma
San J. F. Miguel, M. V. Mateos

17. Lenalidomide in Relapsed or Refractory Multiple Myeloma
Sheeba K. Thomas, Tiffany A. Richards, Donna M. Weber

18. Lenalidomide for Initial Therapy of Newly Diagnosed Multiple Myeloma
Shaji Kumar

V. Current and Future Targets

19. The Role of Heat Shock Protein 90 as a Therapeutic Target for Multiple Myeloma
Constantine S. Mitsiades, Teru Hideshima, Nikhil C. Munshi, Paul G. Richardson, Kenneth C. Anderson

20. The PI3 Kinase/Akt Pathway as a Therapeutic Target in Multiple Myeloma
R. Donald Harvey, Jeannine Silberman, Sagar Lonial

21. The Mammalian Target of Rapamycin and Multiple Myeloma
Patrick Frost, Alan Lichtenstein

22. CDK Inhibitors in Multiple Myeloma
Yun Dai, Steven Grant

23. Fibroblast Growth Factor Receptor 3 and Multiple Myeloma
Victor Hugo Jiménez-Zepeda, A. Keith Stewart

24. Histone Deacetylase Inhibitors in Multiple Myeloma
Teru Hideshima

25. Death Receptors in Multiple Myeloma and Therapeutic Opportunities
Faustino Mollinedo

26. Proteasome Inhibitors as Therapy in Multiple Myeloma
Dharminder Chauhan, Dharminder Ajita, Dharminder Singh, Kenneth Anderson

VI. Supportive Care

27. Pathophysiology of Bone Disease in Multiple Myeloma
Tomer M. Mark, Roger N. Pearse

28. Anemia and Erythropoeitic Growth Factors in Multiple Myeloma
Mark J Sloan, Noopur Raje

29. Percutaneous Vertebroplasty and Balloon Kyphoplasty for the Treatment of Acute Painful Pathologic and Nonpathologic Fractures
Sandra Narayanan, Frank C. Tong

30. The Role of Anatomic and Functional Imaging in Myeloma
Brian G.M. Durie

31. Management of Multiple Myeloma Patients with Renal Dysfunction
Sikander Ailawadhi, Chanan-Khan Asher

VII. Other Plasma Cell Disorders

32. Waldenstrom's Macroglobulinemia
Lijo Simpson, Morie Gertz

33. AL (Immunoglobulin Light-Chain) Amyloidosis
Vaishali Sanchorawala

34. POEMS Syndrome and Other Atypical Plasma Cell Disorders
Angela Dispenzieri

35. Monoclonal Gammopathy of Undetermined Significance
Robert A. Kyle, S. Vincent Rajkumar

Keywords: MEDICAL / Public Health MED078000