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Gullick, William John

EGFR Signaling Networks in Cancer Therapy

Gullick, William John - EGFR Signaling Networks in Cancer Therapy, ebook

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ISBN: 9781597453561
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Table of contents

1. EGFR Signaling Networks

2. EGFR Receptor Family Extracellular Domain Structures and Functions
Antony W. Burgess, Thomas P.J Garrett

3. EGFR family heterodimers in cancer pathogenesis and treatment
Howard M. Stern

4. Structure-function of EGFR kinase domain and its inhibitors
Charles Eigenbrot

5. Internalization and degradation of EGF receptor
Alexander Sorkin

6. Differential dependence of EGFR and ErbB2 on the molecular chaperone Hsp90
Wanping Xu, Len Neckers

7. Activation of STATs 3 and 5 Through the EGFR Signaling Axis
Priya Koppikar, Jennifer Rubin Grandis

8. The intersection of EGFR and the Ras signaling pathway
Marie Wislez, Jonathan M. Kurie

9. PHOSPHOINOSITIDE 3-KINASE ENZYMES AS DOWNSTREAM TARGETS OF THE EGF RECEPTOR
Jan Domin

10. Convergence of EGF Receptor and Src Family Signaling Networks in Cancer
Jessica E. Pritchard, Allison B. Jablonski, Sarah J. Parsons

11. A Molecular Crosstalk between E-cadherin and EGFR Signaling Networks
Julie Gavard, J. Silvio Gutkind

12. Crosstalk Between Insulin-like Growth Factor (IGF) and Epidermal Growth Factor (EGF) Receptors
Marc A. Becker, Douglas Yee

13. Negative regulation of signaling by the EGFR family
Kermit L. Carraway, Lily Yen, Ellen Ingalla, Colleen Sweeney

14. Nuclear ErbB Receptors: Pathways and Functions
Hong-Jun Liao, Graham Carpenter

15. Temporal Dynamics of EGF Receptor Signaling by Quantitative Proteomics
Blagoy Blagoev, Irina Kratchmarova, Jesper V. Olsen, Matthias Mann

16. Computational and Mathematical Modelling of the EGF Receptor System
Colin G. Johnson, Emmet McIntyre, William Gullick

2. EGFR in Tumorigenesis and EGFR Tyrosine Kinase Inhibitors in Cancer Therapy

17. Expression and prognostic significance of the EGFR in solid tumors
Nicola Normanno, Caterina Bianco, Antonella Luca, Luigi Strizzi, Marianna Gallo, Mario Mancino, David S. Salomon

18. Signalling by the EGF receptor in human cancers: accentuate the positive, eliminate the negative
Haley L. Bennett, Tilman Brummer, Paul Timpson, Kate I. Patterson, Roger J. Daly

19. EGFR signaling in invasion, angiogenesis and metastasis
Carol Box, Joanna Peak, Susanne Rogers, Suzanne Eccles

20. Constitutive activation of truncated EGF receptors in glioblastoma
Carol J. Wikstrand, Darell D. Bigner

21. EGFR Mutations, Other Molecular Alterations Related To Sensitivity to EGFR Inhibitors, and Molecular Testing for EGFR-Targeted Therapies in Non-Small Cell Lung Cancer
David A. Eberhard

22. Crosstalk Between COX-2 and EGFR: A Potential Therapeutic Opportunity
Andrew J. Dannenberg, Kotha Subbaramaiah

23. Cellular sensitivity to EGF receptor inhibitors
Stuart Thomson, John D. Haley, Robert Yauch

24. Utilizing combinations of molecular targeted agents to sensitize tumor cells to EGFR inhibitors
Elizabeth Buck, Alexandra Eyzaguirre, Kenneth K. Iwata

Keywords: Medicine & Public Health, Cancer Research, Oncology

Author(s)
 
Publisher
Springer
Publication year
2008
Language
en
Edition
1
Series
Cancer Drug Discovery and Development
Page amount
11 pages
Category
Medicine, Health Care, Mode
Format
Ebook
eISBN (PDF)
9781597453561

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