Antman, Karen

Molecular Targeting in Oncology

Antman, Karen - Molecular Targeting in Oncology, ebook


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ISBN: 9781597453370
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Table of contents

I.General Strategies for Molecular Targeting in Oncology

1. The Cell Cycle
Chad D. Knights, Richard G. Pestell

2. mTOR
John B. Easton, Peter J. Houghton

3. Ras/Raf/MEK Inhibitors
Joseph A. Sparano

4. 17-AAG
Len Neckers, Percy Ivy

5. The Cancer Epigenome
Sam Thiagalingam, Douglas V. Faller

II.Molecular Targeting for Specific Disease Sites

6. Molecular Targeting in Upper Gastrointestinal Malignancies
Scott Wadler

7. Molecular Targeting of Colorectal Cancer
Mark L. Sundermeyer, Alfonso Bellacosa, Neal J. Meropol

8. Molecular Targeting in Hepatocellular Carcinoma
Jonathan D. Schwartz, Josep M. Llovet

9. Molecularly Targeted Therapy in Pancreatic Cancer
Anupama Goel, Peter Kozuch

10. Untargeted Use of Targeted Therapy
Cheryl Ho, Angela M. Davies, Primo N. Lara, O. Gautschi, P.C. Mack, Paul H. Gumerlock, David R. Gandara

11. Renal Cell Carcinoma
Olwen Hahn, Walter Stadler

12. Targeted Therapies for Prostate Cancer
Elisabeth I. Heath, Michael A. Carducci

13. Molecular Targets in Ovarian Cancer and Endometrial Cancer
Nilofer S. Azad, Gisele Sarosy, Elise C. Kohn

14. Targeted Therapy For Breast Cancer
Deena M. Atieh, Linda T. Vahdat

15. Melanoma
Akshay Gupta, John M. Kirkwood

III.Classes of Drugs for Molecular Targeting in Oncology

16. Antibody Therapy of Cancer
Hossein Borghaei, Liat Binyamin, Igor Astsaturov, Louis M. Weiner

17. Nucleic Acid Therapies for Cancer Treatment
Dan T. Vogl, Alan M. Gewirtz

18. Engineering Oncolytic Measles Viruses for Targeted Cancer Therapy
Takafumi Nakamura, Stephen J. Russell

19. Vaccines as Targeted Cancer Therapy
Miguel-Angel Perales, Jedd D. Wolchok, Howard L. Kaufman

20. Cytokine-Based Therapy for Cancer
Henry B. Koon, Michael B.Atkins

21. Cyclooxygenase-2 as a Target for Cancer Prevention and Treatment
Monica Bertagnolli, Jaye L. Viner, Ernest T. Hawk

IV.Specific Drugs for Molecular Targeting in Oncology

22. Imatinib Mesylate (Gleevec®) and the Emergence of Chemotherapeuticss Drug-Resistant Mutations
Gerald V. Denis

23. Development of a Targeted Treatment for Cancer
John Mendelsohn

24. VEGF Inhibition for Cancer Therapy
Shermini Saini, Herbert Hurwitz

25. Somatostatin Analogue Therapy
M. C. Champaneria, I. M. Modlin, I. Latich, J. Bornschein, I. Drozdov, M. Kidd

V.Challenges in Molecular Targeting in Oncology

26. Patient Selection for Rational Development of Novel Anticancer Agents
Grace K. Dy, Alex A. Adjei

27. Clinical Trial Design with Targeted Agents
Sarita Dubey, Joan H. Schiller

28. How to Define Treatment Success or Failure if Tumors Do Not Shrink
J.J.E.M. Kitzen, M.J.A. de Jonge, J. Verweij

29. Molecular Imaging in Oncology
Lalitha K. Shankar, Anne Menkens, Daniel C. Sullivan

30. Combinations of Molecular-Targeted Therapies
Helen X. Chen, Janet E. Dancey

31. Preclinical Development of Molecularly Targeted Agents in Oncology
Joseph E. Tomaszewski, James H. Doroshow


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Keywords: TECHNOLOGY & ENGINEERING / Biomedical TEC059000

Publication year
Medicine, Health Care, Mode

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