Bukowski, Ronald M.

Renal Cell Carcinoma

Bukowski, Ronald M. - Renal Cell Carcinoma, ebook


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ISBN: 9781597453325
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Table of contents

1. Targeted Therapy for Metastatic Renal Cell Carcinoma: Overview
Ronald M. Bukowski, Robert A. Figlin, Robert J. Motzer

2. Molecular Genetics in Inherited Renal Cell Carcinoma: Identification of Targets in the Hereditary Syndromes
Nadeem Dhanani, Cathy Vocke, Gennady Bratslavsky, W. Marston Linehan

3. Molecular Targets in Renal Tumors: Pathologic Assessment
M. Zhou

4. Interferons and Interleukin-2: Molecular Basis of Activity and Therapeutic Results
Thomas E. Hutson, Snehal Thakkar, Peter Cohen, Ernest C. Borden

5. The Molecular Biology of Kidney Cancer and Its Clinical Translation into Treatment Strategies
William G. Kaelin Jr., Daniel J. George

6. VEGF: Biologic Aspects and Clinical Approaches
W. Kimryn Rathmell, Brian I. Rini

7. VEGF and PDGF Receptors: Biologic Relevance and Clinical Approaches to Inhibition
John S. Lam, Robert A. Figlin, Arie S. Belldegrun

8. Sunitinib and Axitinib in Renal Cell Carcinoma
Robert J. Motzer

9. Sorafenib in Renal Cell Carcinoma
Saby George, Ronald M. Bukowski

10. Additional Tyrosine Kinase Inhibitors in Renal Cell Carcinoma
Brian I. Rini

11. Integrin ?5?1 as a Novel Therapeutic Target in Renal Cancer
Vanitha Ramakrishnan, Vinay Bhaskar, Melvin Fox, Keith Wilson, John C. Cheville, Barbara A. Finck

12. Carbonic Anhydrase IX: Biology and Clinical Approaches
Brian Shuch, Arie S. Belldegrun, Robert A. Figlin

13. Monoclonal Antibody G250 Recognizing Carbonic Anhydrase IX in Renal Cell Carcinoma: Biological and Clinical Studies
J. C. Oosterwijk-Wakka, Otto C. Boerman, Peter F. A. Mulders, Egbert Oosterwijk

14. Chemokines in Renal Cell Carcinoma: Implications for Tumor Angiogenesis and Metastasis
Karen L. Reckamp, Robert A. Figlin, Robert M. Strieter

15. PI3K/Akt/mTOR Pathway: A Growth and Proliferation Pathway
Daniel Cho, James W. Mier, Micheal B. Atkins

16. EGFR and HER2: Relevance in Renal Cell Carcinoma
Eric Jonasch, Cheryl Lyn Walker

17. Proteasome–NF?B Signaling Pathway: Relevance in RCC
Jorge A. Garcia, Susan A. J. Vaziri, Ram Ganapathi

18. The Role of Hepatocyte Growth Factor Pathway Signaling in Renal Cell Carcinoma
Benedetta Peruzzi, Jean-Baptiste Lattouf, Donald P. Bottaro

19. Smac/DIABLO: A Proapoptotic Molecular Target in Renal Cell Cancer
Yoichi Mizutani, Akihiro Kawauchi, Benjamin Bonavida, Tsuneharu Miki

20. EphA2: A Novel Target in Renal Cell Carcinoma
Mayumi Kawabe, Christopher J. Herrem, James H. Finke, Walter J. Storkus

21. Restoring Host Antitumoral Immunity: How Coregulatory Molecules Are Changing the Approach to the Management of Renal Cell Carcinoma
Brant A. Inman, Xavier Frigola, Haidong Dong, James C. Yang, Eugene D. Kwon

22. The Role of Gangliosides in Renal Cell Carcinoma
Philip E. Shaheen, Ronald M. Bukowski, James H. Finke

23. Tumour Necrosis Factor — Misnomer and Therapeutic Target
Marina Parton, Tanya Das, Gaurisankar Sa, James Finke, Tim Eisen, Charles Tannenbaum

24. Molecular Markers for Predicting Prognosis of Renal Cell Carcinoma
Mark Nogueira, Hyung L. Kim

25. Adjuvant Therapy for Renal Cell Carcinoma: Targeted Approaches
A. Karim Kadar, Christopher G. Wood

Keywords: Medicine & Public Health, Oncology, Nuclear Medicine

Publication year
Page amount
524 pages
Medicine, Health Care, Mode

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