Teicher, Beverly A.
Antiangiogenic Agents in Cancer Therapy
I. Basic Biology of Angiogenesis
1. Vascular Endothelial Growth Factor Family and Its Receptors
Daniel J. Hicklin
2. The Cycle Between Angiogenesis, Perfusion, and Hypoxia in Tumors
Mark W. Dewhirst, Yiting Cao, Gordana Vlahovic
3. The Role of Integrins in Tumor Angiogenesis
Aparna R. Aiyer, Judith A. Varner
4. Tumor Endothelial Cell Abnormalities
Andrew C. Dudley, Michael Klagsbrun
5. The Extracellular Matrix and VEGF Processing
Sunyoung Lee, M. Luisa Iruela-Arispe
6. Endothelial Precursor Cells
Rebecca G. Bagley
7. Role of Pericytes in Angiogenesis
Chunhua Lu, Anil K. Sood
8. Newer Vascular Targets
Beverly A. Teicher
9. Chemokines in Angiogenesis
Michael P. Keane, John A. Belperio, Robert M. Strieter
10. Angiopoietin/Tie2 Signaling Regulates Tumor Angiogenesis
Hanako Kobayashi, Laura M. DeBusk, P. Charles Lin
11. Imaging Angiogenesis
Sanjeeva P. Kalva, Saravanan Namasivayam, Dushyant Vasuedeo Sahani
12. Tumor Blood Vessels
Yineng Fu, Janice A. Nagy, Ann M. Dvorak, Harold F. Dvorak
13. Lymphatic System in the Pathology of Cancer
Bronislaw Pytowski
II. Translational Research in Tumor Angiogenesis
14. VEGF in the Adult
Arindel S.R. Maharaj, Patricia A. D’Amore
15. Normalization of Tumor Vasculature and Microenvironment
Rakesh K. Jain, Tracy T. Batchelor, Dan G. Duda, Christopher G. Willett
16. Metronomic Low-Dose Antiangiogenic Chemotherapy in Mice and Man
Robert S. Kerbel, U. Emmenegger, S. Man, R. Munoz, C. Folkins, Y. Shaked
17. Small-Molecule Vascular Disrupting Agents in Cancer Therapy
Dietmar W. Siemann, Michael R. Horsman
18. Normalization of Tumor Vasculature and Improvement of Radiation Response by Antiangiogenic Agents
Erin Mendoza, Randy Burd, Phyllis Wachsberger, Adam P. Dicker
19. Challenges in Translating Antiangiogenic Therapy from the Bench to Bedside
Lee M. Ellis, Nikolaos A. Dallas, George van Buren, Sherry Lim, Ling Xia, Fan Fan, Michael J. Gray
20. Regulation of Angiogenesis in Cancer and Its Therapeutic Implications
Liangfeng Han, Annaka M. Lorincz, Saraswati Sukumar
III. Antiangiogenic Therapy in the Clinical Trial Results and Future Directions
21. Angiogenesis and Angiogenesis Inhibition in Sarcomas
Steven DuBois, George Demetri
22. Antiangiogenesis Agents in Colorectal Cancer
Axel Grothey
23. Antiangiogenic Therapy for Primary CNS Tumors
Katherine E. Warren, Howard A. Fine
24. Angiogenesis Inhibitors for the Treatment of Lung Cancer
Monique B. Nilsson, Emer O. Hanrahan, John V. Heymach
25. Antiangiogenic Therapy of Renal Cell Carcinoma
Michael S. Gordon, Scot W. Ebbinghaus
26. Antiangiogenesis Therapies in Gynecologic Malignancies
Robert A. Burger
27. Antiangiogenic Agents in Myeloid Malignancies
Magda Melchert, Alan F. List
28. Angiogenesis in Malignant and Non-Malignant Pediatric Tumors
Domenico Ribatti, Mirco Ponzoni
29. Prognostic and Predictive Significance of Surrogate Biomarkers of Angiogenesis
Raffaele Longo, Francesco Torino, Giampietro Gasparini
30. Endpoints for the Determination of Efficacy of Antiangiogenic Agents in Clinical Trials
Joseph Paul Eder, Dan S. Zuckerman
31. The Role of Imaging in the Clinical Development of Antiangiogenic Agents
Andrew R. Clamp, Gordon C. Jayson
Keywords: Biomedicine, Cancer Research, Oncology, Surgical Oncology, Pharmacology/Toxicology
- Author(s)
- Teicher, Beverly A.
- Ellis, Lee M.
- Publisher
- Springer
- Publication year
- 2008
- Language
- en
- Edition
- 2
- Series
- Cancer Drug Discovery and Development
- Page amount
- 577 pages
- Category
- Medicine, Health Care, Mode
- Format
- Ebook
- eISBN (PDF)
- 9781597451840