Runge, Marschall S.

Principles of Molecular Medicine

Runge, Marschall S. - Principles of Molecular Medicine, ebook


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Table of contents

I. Genetics

1. Mendelian Inheritance
Bruce R. Korf

2. Nontraditional Inheritance
Shawn E. McCandless, Suzanne B. Cassidy

3. Identifying Causal Genetic Factors
Christopher I. Amos, John S. Witte, William G. Newman

4. Cancer Genetics and Molecular Oncology
Sharon E. Plon

5. Pharmacogenetics
Renee E. Edkins, Dennis J. Cheek

6. Hemophilia as a Model Disease for Gene Therapy of Genetic Disorders
Jay Lozier

7. Genetic Counseling
Robin L. Bennett

8. Animal Models in Biomedical Research
Robert W. Williams

9. Ethical, Legal, and Social Implications
Marcia Riper

II. Cardiology

10. Congenital Heart Disease
Lazaros K. Kochilas, Alvin J. Chin

11. Inherited Cardiomyopathies
Carolyn Y. Ho, Christine E. Seidman

12. Heart Failure
Clive J. Lewis, Federica Del Monte, Sian E. Harding, Roger J. Hajjar

13. Aortic Diseases
Saumya Das, James L. Januzzi, Eric M. Isselbacher

14. Atherosclerotic Coronary Disease
Robert E. Gerszten, Anthony Rosenzweig

15. Lipid Metabolism and Coronary Artery Disease
Mason W. Freeman

16. Hypertension
Khurshed A. Katki, Donald J. Dipette

17. Cardiac Hypertrophy
Thomas Force, Jeffery D. Molkentin

18. Arrhythmias
Barry London

19. Genomics
Calum A. Macrae, Christopher J. O’donnell

20. Cardiovascular Gene Therapy
David A. Dichek

III. Pulmonary Diseases

21. Idiopathic Interstitial Pneumonias
Talmadge E. King

22. Asthma
Stephen T. Holgate, Gordon Dent, Mark G. Buckley

23. Pulmonary Emphysema
Steven D. Shapiro

24. Pulmonary Hypertension
Brian Fouty, David M. Rodman

25. Acute Lung Injury
Michelle Ng Gong, David C. Christiani

26. Primary Ciliary Dyskinesia
Peadar G. Noone, Maimoona Zariwala, Michael R. Knowles

27. Cystic Fibrosis
Scott H. Donaldson, Richard C. Boucher

28. Gene Therapy for Lung Diseases
Eric W.F.W. Alton, Jane C. Davies, Duncan M. Geddes

29. Sarcoidosis
Kelly D. Chason, Stephen L.

30. Disorders of Pulmonary Surfactant Homeostasis
Jeffrey A. Whitsett, Susan E. Wert, Bruce C. Trapnell

IV. Endocrinology

31. Mechanisms of Hormone Action
Stephen R. Hammes, Carol A. Lange, Michael J. McPhaul

32. Diabetes Mellitus
William L. Lowe

33. Pituitary Function and Neoplasia
Shlomo Melmed

34. Growth Hormone Deficiency Disorders
John A., Amy Potter

35. Thyroid Disorders
Peter Kopp

36. Disorders of the Parathyroid Gland
Andrew Arnold, Michael A. Levine

37. Congenital Adrenal Hyperplasia
Robert C. Wilson, Maria I. New

38. Adrenal Diseases
Richard J. Auchus, William E. Rainey, Keith L. Parker

39. Multiple Endocrine Neoplasia Type 1
Rajesh V. Thakker

40. Multiple Endocrine Neoplasia Type 2
Robert F. Gagel, Sarah Shefelbine, Hironori Hayashi, Gilbert Cote

41. Disorders of Sex Determination and Differentiation
Charmian A. Quigley

42. Sex Chromosome Disorders
Andrew R. Zinn

43. Disorders of Pubertal Development
Tomonobu Hasegawa

44. Defects of Androgen Action
Michael J. McPhaul

45. Molecular Endocrinology of the Testis
Marco Marcelli, Glenn R. Cunningham, José M. Garcia, Kirk C. Lo, Dolores J. Lamb

46. Ovarian Diseases
Elizabeth A. McGee, Tammy L. Loucks

V. Metabolic Disorders

47. Gastrointestinal Regulation of Food Intake
Patrick Tso, Min Liu

48. Cellular Regulation of Lipolysis
Allan Green

49. Fat-Induced Insulin Resistance and Atherosclerosis
Guenther Boden

50. Metabolic and Molecular Aspects of Sarcopenia
W. Todd Cade, Kevin E. Yarasheski

51. Adipose Tissue Development and Metabolism
Sheila Collins, Yushi Bai, Jacques Robidoux

VI. Gastroenterology

52. Hepatitis C
Johnson Yiu-Nam Lau, Jane Wing-Sang Fang, Masashi Mizokami, Robert G. Gish, Teresa L. Wright

53. Molecular Diagnostics in Hepatitis B
Scott Bowden, Stephen Locarnini

54. Hereditary Hemochromatosis
Francesca Ferrara, Elena Corradini, Antonello Pietrangelo

55. Pancreatic Exocrine Dysfunction
David C. Whitcomb, Jonathan A. Cohn

56. Small and Large Bowel Dysfunction
Deborah C. Rubin

57. The Molecular Mechanisms of Helicobacter pylori-Associated Gastroduodenal Disease
Peter B. Ernst

VII. Nephrology

58. Nitric Oxide Synthase and Cyclooxygenase in the Kidneys
Christopher S. Wilcox

59. Hypertension and Sodium Channel Turnover
Douglas C Eaton, Bela Malik, He-Ping Ma

60. Nephrogenic Diabetes Insipidus st[Water and Urea Transport
Jeff M. Sands, Deniel G. Bichet

61. Glomerulonephritis and Smad Signaling
Hui Y. Lan, Richard J. Johnson

62. Interstitial Nephritis
Carla Zoja, Giuseppe Remuzzi

63. The Pathophysiology of Acute Renal Failure
Didier Portilla, Gur P. Kaushal, Alexei G. Basnakian, Sudhir V. Shah

64. Loss of Lean Body Mass in Uremia
S. Russ Price, William E. Mitch

65. Mechanisms of Renal Allograft Rejection
Daniel R. Goldstein, Anirban Bose, Fadi G. Lakkis

VIII. Musculoskeletal

66. Muscle Development and Differentiation
Eric N. Olson

67. Skeletal Muscle Structure and Function
Elizabeth M. Mcnally, Karen A. Lapidos, Matthew T. Wheeler

68. Stem Cells and Muscle Regeneration
Cindy M. Martin, Thomas J. Hawke, Daniel J. Garry

69. Skeletal Muscle Hypertrophy and Response to Training
Zhen Yan, R. Sanders Williams

70. Muscular Dystrophies
Peter B. Kang, Louis M. Kunkel

71. Rhabdomyosarcomas
Stephen J. Tapscott

IX. Oncology

72. Apoptosis
W. Stratford May, Xingming Deng

73. Colorectal Cancer
Satya Narayan

74. Breast Cancer
Yi Huang, Nancy E. Davidson

75. Lung Cancer
Lei Xiao

76. Discoveries and Frontiers in Prostate Cancer Translational Sciences
Jonathan W. Simons

77. Cutaneous Melanoma
R. Jackson Moira, P. Sugrue Stephen

78. Applications of Gene Expression Profiling to the Study of Malignant Gliomas
Anthony T. Yachnis, Henry V. Baker

79. Acute Myeloid Leukemias
Iris T. Chan, D. Gary Gilliland

80. Acute Lymphoblastic Leukemia
Alexander E. Perl, Donald Small

81. Chronic Myelogenous Leukemia
Brian J. Druker

82. Non-Hodgkin’s Lymphoma and Chronic Lymphocytic Leukemia
Ayad M. Al-Katib, Anwar N. Mohamed

83. Multiple Myeloma
Kenneth H. Shain, William S. Dalton

84. HIV-1, AIDS, and Related Malignancies
Maureen M. Goodenow, James J. Kohler

X. Hematology

85. Disorders of the Red Cell Membrane
Jean Delaunay, Gordon W. Stewart

86. Paroxysmal Nocturnal Hemoglobinuria
Bruno Rotoli, Khedoudja Nafa, Antonio M. Risitano

87. Iron Metabolism
Nancy C. Andrews

88. Correction of Genetic Blood Defects by Gene Transfer
Marina Cavazzana-Calvo, Salima Hacein-Bey-Abina, Adrian J. Thrasher, Philippe Leboulch, Alain Fischer

89. Bone Marrow Failure Syndromes
J. Eric Turner, Thomas C. Shea

90. Coagulation Disorders
Stephan Moll, Gilbert C. White

91. Advances in Transfusion Safety
Lorna M. Williamson, Jean-Pierre Allain

XI. Immunology And Infectious Diseases

92. Immunomodulation
Juan C. Gea-Banacloche

93. HIV Molecular Biology, Treatment Resistance
Frank Maldarelli

94. Cellular and Molecular Aspects of Pneumonia
Tom Poll, Marcus J. Schultz

95. Molecular Pathogenesis of Fungal Infections
Brahm H. Segal

XII. Dermatology

96. Psoriasis
James T. Elder

97. Atopic Dermatitis
Kefei Kang, Donald Y. M. Leung, Kevin D. Cooper

98. Pemphigus Foliaceus, Pemphigus Vulgaris, Paraneoplastic Pemphigus, Bullous Pemphigoid, Herpes Gestationis, and Cicatricial Pemphigoid
Ning Li, David S. Rubenstein, Zhi Liu, Luis A. Diaz

99. Systemic Lupus Erythematosus
Amr H. Sawalha, Luis A. Diaz, John B. Harley

100. Systemic Sclerosis
Chris T. Derk, Sergio A. Jimenez

101. Diseases With Signaling and Transcriptional Abnormalities
David S., Amy Stein, Lowell A.

102. Genetic Skin Diseases With Neoplasia
David S. Rubenstein

103. Melanoma and Nevi
Nancy E.

104. Disorders of Hypopigmentation
Julie V. Schaffer, Jean L. Bolognia

105. Epidermolysis Bullosa
Jouni Uitto, Gabriele Richard, Angela M. Christiano

106. Connective Tissue Disorders
Jouni Uitto, Franziska Ringpfeil

107. Genetic Epidermal Diseases
Amy Stein, Lowell A.

108. Genetic Hair and Nail Defects
Marija Tadin-Strapps, Angela M. Christiano

109. Metabolic Genetic DisordersWith Prominent Skin Findings
Christopher B. Mizelle, Lowell A. Goldsmith

110. Heritable Conditions Affecting Tissues of the Oral Cavity
J. Tim Wright

XIII. Neurology

111. The Genetic Basis of Human Cerebral Cortical Malformations
Bernard S. Chang, Christopher A. Walsh

112. Muscular Dystrophies
Eric P. Hoffman, Erynn S. Gordon

113. Channelopathies of the Nervous System
Stephen C. Cannon

114. Charcot-Marie-Tooth Disease and Related Peripheral Neuropathies
James R. Lupski

115. Amyotrophic Lateral Sclerosis and Related Motor Neuron Disorders
Robert H. Brown

116. Trinucleotide Repeat Disorders
Huda Y. Zoghbi

117. Parkinson’s Disease
Deepak M. Sampathu, Virginia M.-Y. Lee

118. Genetics and Neurobiology of Alzheimer’s Disease and Frontotemporal Dementias
Peter H. ST. George-hyslop

119. Prion Diseases
Adriano Aguzzi

120. Narcolepsy and Other Neurological Sleep Disorders
Thomas E. Scammell

121. Neurofibromatosis 1 and 2
Gregory J. Esper, David H. Gutmann

122. Axonal Regeneration and Recovery From Chronic Central Nervous System Injury
Stephen M. Strittmatter

XIV. Psychiatry

123. Molecular Mechanisms Regulating Behavior
Kerry J. Ressler, Charles B. Nemeroff

124. The Complex Genetics of Psychiatric Disorders
Ming T. Tsuang, Stephen J. Glatt, Stephen V. Faraone

125. Treating Depression
Marcelo Páez-Pereda, Florian Holsboer

126. Anxiety Disorders
Gregory M. Sullivan, Jack M. Gorman

127. Trauma Spectrum Disorders
Christine Heim, J. Douglas Bremner, Charles B. Nemeroff

128. Schizophrenia
Carol A. Tamminga, Deborah C. Medoff, Gunvant Thaker

129. Disorders of Substance Abuse and Dependence
Eric J. Nestler, Jennifer Chao

130. Autism and Related Disorders
Lin Marie Sikich, Thomas H. Wassink, Kevin A. Pelphrey, Joseph Piven

Keywords: Medicine & Public Health, Internal Medicine

Publication year
Page amount
1293 pages
Medicine, Health Care, Mode

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