Molecular Neurosurgery With Targeted Toxins

1. Introduction to Molecular Neurosurgery
Ronald G. Wiley, Douglas A. Lappi

2. Ribosome-Inactivating Proteins
Fiorenzo Stirpe

3. Biochemical, Physiological, and Behavioral Characterizations of the Cholinergic Basal Forebrain Lesion Produced by 192 IgG-Saporin
Jerene J. Waite

4. Basal Forebrain Cholinergic Lesion by 192 IgG-Saporin
Reinhard Schliebs

5. 192 IgG-Saporin-Induced Partial Cortical Cholinergic Deafferentation as a Model for Determining the Interactions Between Brain Aging and Neurodevelopmental Defects in the Cortical Cholinergic Input System
Martin Sarter, John P. Bruno

6. Exploring the Role of Acetylcholine in Primate Cognition Using Me20.4 IgG-Saporin
Rosalind M. Ridley, Harry F. Baker

7. Cortical Cholinergic Deafferentation Induces Aß Deposition
Thomas G. Beach, D. G. Walker, P. E. Potter, L. I. Sue, S. Scott, K. J. Layne, A. J. Newell, P. K. Rauschkolb, M. E. Poston, S. D. Webster, R. A. Durham, M. R. Emmerling, K. Sawada, W. G. Honer, A. Fisher, A. E. Roher

8. Chemical Dissection of Brain Glucoregulatory Circuitry
Sue Ritter, Thu T. Dinh, Kishor Bugarith, Dawna M. Salter

9. Cardiovascular Deficits After Lesions of C1 Adrenergic Neurons With a Saporin-Based Immunotoxin
Patrice G. Guyenet, Ruth L. Stornetta, Ann M. Schreihofer

10. Saporin Conjugates and Pain
Ronald G. Wiley, Douglas A. Lappi

11. The Use of Saporin Conjugates to Dissect Neurons Responsible for Sleep and Wakefulness
Carlos Blanco-Centurion, Dmitry Gerashchenko, Eric Murillo-Rodriguez, Frank Desarnaud, Priyattam J. Shiromani

12. Isolectin IB4-Mediated Cytotoxic Targeting of Sensory Neurons
Lucy Vulchanova, Christopher N. Honda

13. B Fragment of Cholera Toxin Conjugated to Saporin
Peter T. Ohara, Kanwarjit Kelley, Luc Jasmin

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Keywords: MEDICAL / Public Health MED078000