Thyroid Hormone Disruption and Neurodevelopment

Part I. Disruption of Thyroid Hormone Action at Molecular Level

1. Mechanisms for Thyroid Hormone Action in the CNS
Rohit Anthony Sinha, Paul M. Yen

2. Deiodinase and Brain Development
Masami Murakami

3. Brominated Organohalogens and Neurodevelopment: Different Mechanisms, Same Consequence
Kingsley Ibhazehiebo, Toshiharu Iwasaki, Noriyuki Koibuchi

4. Perinatal Infection-Associated Changes in Thyroid Hormone Status, Gut Microbiome, and Thyroid Hormone-Mediated Neurodevelopment
E. M. Sajdel-Sulkowska, M. Bialy, R. Zabielski

5. Disruption of Feedback Regulation of Thyroid Hormone Synthesis/Secretion and Brain Development
Sumiyasu Ishii, Masanobu Yamada

Part II. Animal Models to Study Thyroid Hormone Disruption on Neurodevelopment

6. Animal Models to Study Thyroid Hormone Action in Neurodevelopment
Noriaki Shimokawa, Noriyuki Koibuchi

7. Thyroid Hormone Receptor Mutation and Neurodevelopment
Jens Mittag

8. Using Mouse Genetics to Investigate Thyroid Hormone Signaling in the Developing and Adult Brain
F. Chatonnet, S. Richard, F. Flamant

9. Disruption of Auditory Function by Thyroid Hormone Receptor Mutations
David S. Sharlin

Part III. Thyroid Hormone Disruption and Neurodevelopment: Human Studies

10. The Impact of Maternal Thyrotoxicosis and Antithyroid Drug Exposure on Fetal/Neonatal Brain Development
Ines Donangelo, Gregory A. Brent

11. Deficit in Thyroid Hormone Transporters and Brain Development
Takehiro Suzuki, Takaaki Abe

12. Syndromes of Resistance to Thyroid Hormone and Brain Development
Irene Campi, Paolo Beck-Peccoz

Keywords: Biomedicine, Neurosciences, Endocrinology, Neurology