Tumor Metabolome Targeting and Drug Development

1. Tumor Cell Metabolic Reprogramming and Drug Targeting
Steven B. Kanner

2. Cancer Metabolism: A Nexus of Matter, Energy, and Reactive Oxygen Species
Paul M. Bingham, Shawn D. Stuart, Zuzana Zachar

3. Regulating Mitochondrial Respiration in Cancer
Teresa L. Serafim, Paulo J. Oliveira

4. Regulation of Cancer Cell Metabolism by Hypoxia
Ashleigh Pulkoski-Gross, Nikki A. Evensen, Jian Cao

5. Glucose Metabolism and the Antioxidative Defense System in Cancer Cells: Options for the Application of ROS-based Anticancer Drugs
Gernot Bruchelt, Rupert Handgretinger, Mirjam Weckenmann, Talia Hahn

6. Modulating Autophagy and the “Reverse Warburg Effect”
Maria I. Vaccaro, Claudio D. Gonzalez, Silvia Alvarez, Alejandro Ropolo

7. Metabolic Adaptation in Reprogrammed Cancer Cells
Kevin Marks, Charles Kung

8. Targeting of PFKFB3
Katarina Färnegårdh, Maria Shoshan, Lars Ährlund-Richter

Keywords: Biomedicine, Cancer Research, Metabolomics, Molecular Medicine, Pharmacology/Toxicology