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Melillo, Giovanni

Hypoxia and Cancer

Melillo, Giovanni - Hypoxia and Cancer, ebook

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ISBN: 9781461491675
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Table of contents

Part I. Biology

1. Hypoxia and Breast Cancer Metastasis
Luana Schito, Gregg L. Semenza

2. Hypoxia and the DNA Damage Response
Monica M. Olcina, Ester M. Hammond

3. Emerging Roles of Non-Coding RNAs in the Hypoxic Response
Mircea Ivan, Xiaoling Zhong, Simona Greco, Fabio Martelli

4. Hypoxia and Reactive Oxygen Species
Agnes Görlach

5. Hypoxia and Gene Expression
Maria Carla Bosco, Luigi Varesio

6. Carbonic Anhydrase IX: From Biology to Therapy
Silvia Pastorekova, Claudiu T. Supuran

Part II. Imaging

7. Imaging the Hypoxic Tumor Microenvironment in Preclinical Models
Mary-Keara Boss, Gregory M. Palmer, Mark W. Dewhirst

8. Clinical Imaging of Hypoxia
Michael R. Horsman, Morten Busk, Thomas Nielsen, Marianne Nordsmark, Jens Overgaard

Part III. Therapy

9. Hypoxia, Metastasis, and Antiangiogenic Therapies
Dietmar W. Siemann, Yao Dai, Michael R. Horsman

10. The Unfolded Protein Response and Therapeutic Opportunities
Carly M. Sayers, Souvik Dey, Stacey L. Lehman, Constantinos Koumenis

11. Small Molecules Targeting the VHL/Hypoxic Phenotype
Raymond J. Louie, Mercè Padró, Amato J. Giaccia, Denise A. Chan

12. Hypoxia and Radiation Therapy
Marianne Nordsmark, Jan Alsner, Morten Busk, Jens Overgaard, Michael R. Horsman

13. Prodrug Strategies for Targeting Tumour Hypoxia
William R. Wilson, Kevin O. Hicks, Jingli Wang, Frederik B. Pruijn

14. Exploiting “Hif Addiction” For Cancer Therapy
Nicole D. Fer, Annamaria Rapisarda

15. Clinical Exploitation of Hypoxia
Geoff S Higgins, Adrian L Harris

Keywords: Biomedicine, Cancer Research, Molecular Medicine, Pharmacology/Toxicology, Stem Cells

Author(s)
Publisher
Springer
Publication year
2014
Language
en
Edition
2014
Series
Cancer Drug Discovery and Development
Category
Medicine, Health Care, Mode
Format
Ebook
eISBN (PDF)
9781461491675

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