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Sugiyama, Yuichi

Transporters in Drug Development

Sugiyama, Yuichi - Transporters in Drug Development, ebook

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ISBN: 9781461482291
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Table of contents

1. Membrane Transporters in ADME
Bente Steffansen, Carsten Uhd Nielsen, Birger Brodin

2. In Vitro Kinetic Characterization of Transporter-Mediated Permeability
Bente Steffansen, Anne Sophie Grandvuinet

3. In Vitro Characterization of Interactions with Drug Transporting Proteins
Per Artursson, Pär Matsson, Maria Karlgren

4. In Vivo Characterization of Interactions on Transporters
Hiroyuki Kusuhara, Kenta Yoshida, Yuichi Sugiyama

5. Applications of Targeted Proteomics in ADME for IVIVE
Larissa M. Balogh, Yurong Lai

6. Prediction of Hepatic Transporter-Mediated Drug–Drug Interaction from In Vitro Data
Kazuya Maeda, Yuichi Sugiyama

7. Accounting for Transporters in Renal Clearance: Towards a Mechanistic Kidney Model (Mech KiM)
Sibylle Neuhoff, Lu Gaohua, Howard Burt, Masoud Jamei, Linzhong Li, Geoffrey T. Tucker, Amin Rostami-Hodjegan

8. Analysis of Intestinal Transporters
Ikumi Tamai, Takeo Nakanishi

9. Analysis of Hepatic Transport Proteins
Kyunghee Yang, Kathleen Köck, Kim L. R. Brouwer

10. Analysis of Renal Transporters
Frans G. M. Russel, Rosalinde Masereeuw

11. The Role of Transporters in Drug Development: Regulatory Science Perspectives from the FDA
Lei Zhang, Shiew-Mei Huang

12. Industrial Evaluation of Drug Transporters in ADME
Mitchell E. Taub, Naoki Ishiguro, Olaf Schaefer, Donald J. Tweedie

Keywords: Biomedicine, Pharmaceutical Sciences/Technology, Biomedicine general

Author(s)
 
Publisher
Springer
Publication year
2013
Language
en
Edition
2013
Series
AAPS Advances in the Pharmaceutical Sciences Series
Category
Medicine, Health Care, Mode
Format
Ebook
eISBN (PDF)
9781461482291

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