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Dull, Randal O.

A Case Approach to Perioperative Drug-Drug Interactions

Dull, Randal O. - A Case Approach to Perioperative Drug-Drug Interactions, ebook

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Table of contents

I. Introduction to Drug–Drug Interactions

1. Let’s Start at the Very Beginning: Overcoming Fear and Gaining Mastery of Drug–Drug Interactions
F. Jacob Seagull, Christopher E. Swide, Catherine Marcucci

2. Pharmacodynamic Interactions: Core Concepts
Erica D. Wittwer, Wayne T. Nicholson

3. Pharmacokinetic Interactions: Core Concepts
Erica D. Wittwer, Wayne T. Nicholson

4. A Brief Treatise on the Area Under the Curve
Michael J. Sikora, Barbara Jericho

II. Introduction to Drug–Drug Interactions: Brief Review of Cytochrome P450 (CYP450) Enzymes, Uridine 5'-diphospho-glucuronoslytransferases (UGTs), and Transporters

5. CYP2D6: Where It All Began
John C. Sanders, Rachel Koll, Randal O. Dull

6. CYP2E1: The Anesthesia Enzyme
Benjamin S. Gmelch, Randal O. Dull

7. CYP3A4: The Workhorse
Jennifer DeCou, Nathaniel Birgenheier, Randal O. Dull

8. CYP1A2: The Switch-hitter
Danielle Roussel, Emily Hagn, Randal O. Dull

9. CYP2B: 2B or Not 2B?
Dustin Coyle, Randal O. Dull

10. CYP2C9: The Support Crew I
Byron Douglas Fergerson, Crystal B. Wallentine, Randal O. Dull

11. CYP2C19: The Support Crew II
Barbara Jericho, Alfredo Aguiar, Randal O. Dull

12. Uridine 5′-diphospho-glucuronoslytransferases (UGTs): Conjugating Cousins
Neil B. Sandson

13. The Cytochrome P450 System in Disease States—A Brief Review
Catherine Marcucci

III. Drug–Drug Interactions: Paradigms and Core Concepts

14. P-glycoprotein and Organic Anion-transporting Polypeptide (OATP) Transporters
Dustin Coyle, Erica D. Wittwer, Juraj Sprung

15. The “Fatal Forty”
Neil B. Sandson, Michael P. Hutchens, F. Jacob Seagull, Catherine Marcucci

16. The Six Patterns of Pharmacokinetic Drug–Drug Interactions
Neil B. Sandson, Catherine Marcucci

17. The Problem with the Drug–Drug Interaction Software: A Procrustean Dilemma
Neil B. Sandson, F. Jacob Seagull, Wayne T. Nicholson, Catherine Marcucci

18. Pharmacogenomics
Chad D. Moore, William Hartman, Michael P. Hutchens, Randal O. Dull

19. The Pharmacoepidemiology of Drug Interactions: Why and How They Are Important
Joseph A. Lovely, Stephen Esper, Michael P. Hutchens, Wayne T. Nicholson, Catherine Marcucci

20. The Lawyers Can Read, Too: Cases from the Courtroom
Jessica Voge, David K. Miller

IV. Drug–Drug Interactions Involving Inhalational Anesthetic Agents

21. Introduction
Catherine Marcucci

22. That Sums It Up
James A. Jernigan, James W. Ibinson

23. 1 + 1 + 1 + 1 = ?
Anthony T. Silipo, Raymond M. Planinsic, Erica D. Wittwer, Juraj Sprung, Wayne T. Nicholson

24. A Delayed Surgeon Is a Dismayed Surgeon
Jonathan Anson

25. Relax, It’s Only Gentamicin
Brian Gierl, Ferenc E. Gyulai

26. Jaundice After Surgery
Jonathon E. Kivela, Toby N. Weingarten, Juraj Sprung

27. Everybody Clear?
Nikhli Patel, Barbara Jericho, Randal O. Dull

28. The Hemodynamic Hole
Arun L. Jayaraman, Theresa A. Gelzinis

29. Alpha-2 to the Rescue but Beware Bradycardia
Phillip Adams, Nashaant N. Rizk

30. Hot Stuff!
Cornelius B. Groenewald, Juraj Sprung

V. Drug–Drug Interactions Involving Intravenous Anesthetic Agents

31. Introduction
Catherine Marcucci

32. How to Successfully Occlude an Intravenous Line
Helga Komen, Juraj Sprung, Toby N. Weingarten

33. A Curious Cause of Seizures
Charles Galaviz, Randal O. Dull

34. Magnesium Mama and the Mad Dad
Ana Maria Manrique, Catherine Marcucci, Kathirvel Subramaniam

35. Dexy’s Midnight Spinal
Michael P. Hutchens, Edward A. Kahl, Matthias J. Merkel

VI. Drug–Drug Interactions Involving Local Anesthetics

36. Introduction
Catherine Marcucci

37. Comfortably Numb
Joseph J. Yurigan, Todd M. Oravitz

38. Naturally Occurring and Nasty
Lauren Partyka, Li Meng

39. LOL-LOL: Little Old Lady—Lots of Lido
Kitling M. Lum, Kelly N. Stafford

40. The Spinal Countdown
Audra M. Webber, Franklyn P. Cladis

41. Are Drug–Drug Interactions The Smoking Guns of Local Anesthetic Toxicity? Smoking Gun I
L. Michele Noles

42. Are Drug-Drug Interactions The Smoking Guns of Local Anesthetic Toxicity? Smoking Gun II
L. Michele Noles

43. A Perfect Storm?
J. Andrew Dziewit, Nabil M. Elkassabany

44. Shake Rattle and Roll
Hans P. Sviggum, Juraj Sprung

45. Hello, We Have a Patient With Acute Delirium and We Need an Urgent Psych Consult
Katarina Bojanić, Juraj Sprung, Toby N. Weingarten

46. Fatal Pain Relief
Matthew M. Kumar, Richard Levi Boortz-Marx

47. Lipid Lifesaver
Adrian Pichurko, Guy Weinberg

VII. Drug–Drug Interactions Involving Opioids

48. Introduction
Toby N. Weingarten

49. No ‘Subs’titute for Sobriety
James Hilliard, Kirk Lalwani

50. A Needle and the Damage Done
James Hilliard, Kirk Lalwani

51. Dad’s Not Having Much Pain
Rani Chovatiya, Mehmet S. Ozcan, Randal O. Dull

52. Royal Flush
Kimberly Mauer, Catherine Marcucci, Neil B. Sandson

53. The Worry That’s Always With Us: Afternoon Nap
Syed M. Quadri, Randal O. Dull

54. The Bawling Baby
Angela Kendrick

55. Sleeping Beauty
Hans P. Sviggum, Juraj Sprung

56. Codeine Can’t Do It
Katarina Bojanić, Wayne T. Nicholson, Erica D. Wittwer, Toby N. Weingarten, Juraj Sprung

57. A Shuddering Interaction
Christine A. Kenyon Laundre, Randall Flick, Juraj Sprung

58. Double Indemnity
Lisa Chan, Catherine Marcucci, Neil B. Sandson, Kirk Lalwani

59. Breaking the Codeine
Clint Christensen, Nathan G. Orgain, Randal O. Dull

60. The Ultimate Ultram Primer I: My Mood Is Better, but Boy Do I Hurt!
Toby N. Weingarten, Juraj Sprung

61. The Ultimate Ultram Primer II: I “Haight” Narcotics, but I Hate Seizures More
Bruce T. Dumser, Neil B. Sandson

62. The Ultimate Ultram Primer III: Tremor-dol Trigger in Serotonin Syndrome
Bryan C. Hoelzer, Stephanie Neuman

63. Too Much of a Good Thing
Erica D. Wittwer, Juraj Sprung, Wayne T. Nicholson

VIII. Drug–Drug Interactions Involving Nonopioid Pain Medications

64. Introduction
Toby N. Weingarten

65. Pining for Pete in the Pain Clinic
Steven S. Liu, Toby N. Weingarten, Catherine Marcucci

66. You Do Not Look Well Today, Mon Ami
Kimberly Mauer, Catherine Marcucci, Neil B. Sandson

67. My Headache Is Gone, But My Leg Now Hurts
Jessica D. Lorenz, Juraj Sprung, Wayne T. Nicholson

68. Special ‘K’ase
Lisa Chan, Kirk Lalwani

69. Not Manic About NSAIDS
Allen N. Gustin, Michael J. Bishop

70. Keep It Capped!
Christine M. Formea, Wayne T. Nicholson

71. The ACE Is Not Always High
Wayne T. Nicholson

72. When the Smoke Clears, Relaxation Disappears
Avinash Ramchandani, Julio A. Gonzalez-Sotomayor

73. Befuddled by Aspirin
Melisa N. Weingarten, Juraj Sprung, Toby N. Weingarten

74. You Can’t Trick Us!
Catherine Marcucci, Neil B. Sandson

IX. Drug–Drug Interactions Involving Benzodiazepines and Other Sedatives

75. Introduction
Catherine Marcucci

76. The Worry That’s Always With Us: Now I’m Depressed
Kelly T. Peretich, Raymond M. Planinsic

77. The Worry That’s Always With Us: Tragic but Not Rare
Phillip Adams, Ibtesam A. Hilmi

78. Lack of Sedation
Erica D. Wittwer, Juraj Sprung, Wayne T. Nicholson

79. A Cold Isn’t Going to Slow Me Down
Leelee Thames, Jessica Miller

80. Her Patients Never Wake Up on Time
Toby N. Weingarten, Erica D. Wittwer, Wayne T. Nicholson

81. When Enough Is Now Too Much
Erica D. Wittwer, Juraj Sprung, Wayne T. Nicholson

82. The Distressed Daughter
Jennifer Egan, Kirk Lalwani, Catherine Marcucci

83. Check Check and Double Check
Catherine Marcucci, Neil B. Sandson

84. Doggone It—The Case Is Cancelled
Erica D. Wittwer, Wayne T. Nicholson, Corinne Wisdo, Catherine Marcucci

85. Noct’ Out
Michael Wollenberg, Kirk Lalwani

86. Predisposed to Doze
Erica D. Wittwer, Juraj Sprung, Wayne T. Nicholson

87. Synergistic Sedation
Michael P. Hutchens, Paul Schipper, Catherine Marcucci

X. Drug–Drug Interactions Involving Neuromuscular Blockade Agents

88. Introduction
David G. Metro

89. Blocked Again: Effects of Repeated Doses of Succinylcholine
Matthew Patrick Feuer, Thomas M. Chalifoux

90. Irreversibility Sux
Joseph C. Shy, David G. Metro

91. Keep an “Ion” the Twitches
Brian Gierl, Ferenc E. Gyulai

92. A Reversal of Misfortune
Thomas N. Talamo, Richard J. Kuwik

93. Stop Moving
Michael D. Olson, Randall Flick

94. There’s Just Not Enough Roc in the World
Tammara S. Goldschmidt, Randal O. Dull

95. Slow Sux I: A Lengthy Wake-up Period After Electroconvulsive Therapy
Jennifer A. Rabbitts, Juraj Sprung

96. Slow Sux II: I Remember Reviewing This for the Boards
Andrew Oken, Scott Richins

97. Slow Sux III: Where Did the Twitches Go?
Katarina Bojanić, Juraj Sprung, Toby N. Weingarten

98. Weakened All Weekend
Daniel W. Johnson

99. The Patient Who Could Not Raise Her Head
Nicole L. Varela, Toby N. Weingarten, Juraj Sprung

100. An Unexpected Wait
Michael W. Best, Shawn T. Beaman

101. Diabolical Cough Syrup
Melisa N. Weingarten, Juraj Sprung, Toby N. Weingarten

XI. Drug–Drug Interactions Involving Antibiotics and Antifungals

102. Introduction
Catherine Marcucci

103. Full Stop
Norah Janosy

104. Flummoxed by the FLOX
Janice Kim

105. Tales of Terror
Arun Subramanian, Juraj Sprung

106. Too Low To Go
Catherine Marcucci, Neil B. Sandson

107. A Fungal Story
Jerusha Taylor, Ansgar M. Brambrink

108. Rejection Protection Turned Kidney Killer
Erica D. Wittwer, Juraj Sprung, Christine M. Formea

109. Can’t Get Well
Michael J. Sikora, Barbara Jericho, Randal O. Dull

110. Linezolid (I): Be “VREy” Careful
Bruce T. Dumser

111. Linezolid (II): Hyper and Hot
Erica D. Wittwer, Toby N. Weingarten, Juraj Sprung

112. Not Sweet At All
Mayumi Horibe, Michael J. Bishop

113. Where Did All the Sugar Go?
Nicole L. Varela, Federica Scavonetto, Toby N. Weingarten, Juraj Sprung

114. Exposed! (Part 1)
L. Michele Noles, Catherine Marcucci

115. Exposed! (Part 2)
L. Michele Noles, Catherine Marcucci

116. Seizures on 5 West
Elizabeth Duggan, Nabil M. Elkassabany

XII. Drug–Drug Interactions Involving Cardiovascular Medications

117. Introduction
Michael P. Hutchens

118. Riding the Rollercoaster
Catherine Marcucci, Erica D. Wittwer, Juraj Sprung

119. A Pressing Need for Vasopressin!
Erin B. Payne, Anna Dubovoy

120. Too Young to Die
Catherine Marcucci

121. A Widening Gyre
Edward A. Kahl, Michael P. Hutchens

122. Misusing Mom’s Meds
Pulsar Li, Steven L. Orebaugh

123. If the Patient Has No Renal Failure, Why Is Her Potassium So High?
Jennifer A. Rabbitts, Wayne T. Nicholson, Juraj Sprung

124. Prazosin and the PTSD Paratrooper
Allen N. Gustin, Michael J. Bishop

125. Nicardipine Notes
Nenna Nwazota, Randal O. Dull

126. Hypotension Harry
Matthew Hart, Bryan J. Read, Wayne T. Nicholson, Toby N. Weingarten

127. Too Slow to Flow
Scott W. Cantwell, Toby N. Weingarten, Juraj Sprung

128. Better Sleep but Slower Heart
Erica D. Wittwer, Juraj Sprung

129. Extreme Blood Pressure After Ephedrine: Should We Rule Out Pheochromocytoma?
Erica D. Wittwer, Juraj Sprung, Wayne T. Nicholson

130. Heart-Stopping Treatment
Erica D. Wittwer, Toby N. Weingarten, Juraj Sprung

131. Induction Crashes: Are There Clues in the Ashes?
Dawn L. Baker, L. Lazarre Ogden

132. The Wakeup Call: 2AM Trauma
Devin C. Tang, Nabil M. Elkassabany

133. Falling Down
Scott Kennedy, Norman A. Cohen

134. A Hidden Drug
Helga Komen, Toby N. Weingarten, Juraj Sprung

135. I’m Listening, I’m Listening
Catherine Marcucci, Jerusha Taylor, Ansgar M. Brambrink, Neil B. Sandson

136. Jump Start My Heart
Katarina Bojani, Juraj Sprung, Toby N. Weingarten

137. The Statin Trilogy (I): ‘Statin’ from the Beginning
Brian Mitchell

138. The Statin Trilogy (II): Tripped and Fell at the Train ‘Statin’
Brian Mitchell

139. The Statin Trilogy (III): Welcome to the United ‘Statins’ of America
Brian Mitchell

140. Be Still, My Beating Heart
Branka Polić, Julije Meštrović, Toby N. Weingarten, Juraj Sprung

141. The Nice Niece
Michael P. Hutchens, Catherine Marcucci

142. Cyclo Killer: Qu’est-ce que c’est?
Jeff Chen, Michael P. Hutchens, Wayne T. Nicholson

143. Blurry-Eyed with Rapid Heart Beats
William A. Shakespeare, Juraj Sprung

XIII. Drug–Drug Interactions Involving Coagulation Modifiers

144. Introduction
Catherine Marcucci

145. Seize the Day
Roman M. Sniecinski, Erica D. Wittwer, Kenichi Tanaka, James Zaidan

146. The Third and Final Complication
Daniel W. Johnson

147. An Interaction with the Furniture
Heather Norvelle, Ines P. Koerner

148. Macrolide Mishap for Little Miss Muffett
Elizabeth Pedigo

149. From Asymptomatic to Symptomatic: A Cause of Nosebleed
Joško Markić, Julije Meštrović, Juraj Sprung

150. The Consequences of Not Following a Cardiac Diet
Kristen B. McCullough, Wayne T. Nicholson

151. Clopidogrel (I): Bagel Brunch
Ann Marie Canelas, Randal O. Dull

152. Clopidogrel (II): Conferring over the Kung Pao
Catherine Marcucci, Neil B. Sandson

XIV. Drug–Drug Interactions Involving Immunosuppressants, Antiemetics, and Chemotherapy

153. Introduction
Catherine Marcucci

154. Beaned
Matthew Hart, Michael P. Hutchens

155. Addisonian Adjustment
Catherine Marcucci, Neil B. Sandson

156. Tea Time
Nikki Jaworski

157. No Fits at Uffizi
Michael P. Hutchens, Christine M. Formea

158. Quit Steroids Quit Kidneys
Toby N. Weingarten, Wayne T. Nicholson, Christine M. Formea

159. The Fall Guy (I)
Catherine Marcucci, Neil B. Sandson

160. The Fall Guy (2)
Catherine Marcucci, Neil B. Sandson

161. The Topic of the Day
Catherine Marcucci

162. Bounce Back
Erica D. Wittwer, Wayne T. Nicholson, Juraj Sprung

163. Call the Cath Lab!
Anna Dubovoy, Erin B. Payne

164. The Imatinib Inquiry: A Theoretical Case (for Now)
Stephen J. Gleich, Erica D. Wittwer, Juraj Sprung, Nicole Henwood

165. A HAART-breaking Tale
Dean Laochamroonvorapongse, Kirk Lalwani

XV. Drug–Drug Interactions Involving Neuropsychiatric Drugs

166. Introduction
Neil B. Sandson

167. Phenytoin (I): Going Crazy!
Sara M. Skrlin, Ansgar M. Brambrink

168. Phenytoin (II): The Wrong Drug for the Schizophrenic
Melisa N. Weingarten, Juraj Sprung, Toby N. Weingarten

169. Dizzy and Depressed
William A. Shakespeare, Juraj Sprung

170. The Funeral Is on Monday
Elizabeth Macri, Ansgar M. Brambrink, Neil B. Sandson

171. This Antacid Is Making Me Sick!
Arun Subramanian, Toby N. Weingarten, Juraj Sprung

172. Young at Heart
Catherine Marcucci

173. Shiver Yes, Die No
Ahmed F. Zaky, Michael J. Bishop

174. Clip and Dip
David W. Barbara, Randall Flick, Juraj Sprung

175. Blue Fog
Toby N. Weingarten, Wayne T. Nicholson, Juraj Sprung

176. Confiscated Contraceptives
Erica D. Wittwer, Juraj Sprung, Wayne T. Nicholson

177. Gotta Love Derm
Jonathan Anson, Richard C. Month

178. Desperate for a Drink
Erica D. Wittwer, Juraj Sprung, Wayne T. Nicholson

XVI. Drug–Drug Interactions Involving QT-Prolonging DDIs

179. Introduction
Matthew DeCaro

180. Delusion at Heart
Arun Subramanian, Toby N. Weingarten, Juraj Sprung

181. At Long Last
Kristen B. McCullough, Wayne T. Nicholson

182. Metha-don’t!
Bryan C. Hoelzer, Juraj Sprung, Wayne T. Nicholson

183. Flash Fire
Michael P. Hutchens, Catherine Marcucci, Neil B. Sandson

184. I Am Dizzy When I Stand Up
Tasha L. Welch, Toby N. Weingarten, Juraj Sprung

XVII. Drug–Drug Interactions Involving Foods and Nutrition

185. Introduction
Kevin W. Cleveland, David G. Metro

186. High Fat Diet (I): No Juice For The Ketotic Kid
Denise M. Hall Burton, Miya Asato, Charles Boucek

187. Protein Huffing and Puffing
Brian C. Bane, James Gordon Cain

188. Salty Sam
Robert Scott Lang, Li Meng

189. A Peak Potassium Problem
Justin McCray, Steven L. Orebaugh

190. Awake?
Nicole Scouras, David G. Metro

191. Tropical Punch Packing a Real Knockout
Brian Blasiole, Shawn T. Beaman

192. When the Fire Won’t Go Out
Thomas P. Pontinen, Randal O. Dull

193. Peppermint Patty
Ryan D. Ball, Karen Boretsky

194. From Bleeding Gums to Green Thumbs: A True Story
Audra M. Webber, Patricia L. Dalby

195. Delicious but Malicious
Eric Fox, Kirk Lalwani

196. I Just Can’t Lick This Problem
Koshy M. Mathai, Michael P. Hutchens, Robert G. Krohner

197. Sommelier’s Surprise
Charles Lin, Joseph F. Talarico

198. Dairy Carefully
Kristin Ondecko Ligda, Erin A. Sullivan

199. Cold and Sick, Sick and Cold
A. Murat Kaynar, Nikhil K. Bhatnagar

200. TPN (I): A Review and Two Interactions
Lavinia Kolarcyzk, Patrick J. Forte

201. TPN (II): A Traumatic Case of Increased Metabolism
Erica D. Wittwer, Wayne T. Nicholson, Juraj Sprung

202. Skin and Bones
Mariam M. El-Baghdadi, Ibtesam A. Hilmi

203. Enough to Make You Sick
John Hache, Thomas M. Chalifoux

204. Determined and Desperate to Diet
Lisa Chan, Kirk Lalwani

XVIII. Drug–Drug Interactions Involving Spices and Supplements

205. Introduction
Kirk Lalwani

206. Caffeine Crash
Brian Gierl, Ryan Romeo

207. Sad Sequelae
Stacy L. Fairbanks

208. The Scary Side of Ginkgo biloba Is No Match for an Anesthesia Superstar: Seizures
Shreya Patel, Kirk Lalwani

209. The Scary Side of Ginkgo biloba Is No Match for an Anesthesia Superstar: Sugar
Shreya Patel, Kirk Lalwani

210. The Scary Side of Ginkgo biloba Is No Match for an Anesthesia Superstar: Subdural
Shreya Patel, Kirk Lalwani

211. “Khat” Unaware
Brian D. Tompkins, Kirk Lalwani

212. Pain on the Plane
Lei Wu, Kirk Lalwani

213. Ca va, c’est Kava
Solina Tith, Kirk Lalwani

214. Summertime and the Herbals are Hot
Jessica Miller, Leelee Thames

215. Garlic I: More Than Just Bad Breath
Vincent Lew, Kirk Lalwani

216. Garlic II: A Girl Named Allicin
Vincent Lew, Kirk Lalwani

217. “Danshen” the Night Away
Tara C. Carey, Kirk Lalwani

218. Caught Yellow-Handed
Giorgio Veneziano, Michael Mangione

219. St. John: Not Such a Saint
Heather Norvelle, Ines P. Koerner

220. Hearing the News
Nikki Jaworski

Keywords: Medicine & Public Health, Anesthesiology, Intensive / Critical Care Medicine, Pharmacy, Surgery

Editor
 
 
 
 
 
 
 
 
 
 
 
 
Publisher
Springer
Publication year
2015
Language
en
Edition
1
Page amount
1064 pages
Category
Medicine, Health Care, Mode
Format
Ebook
eISBN (PDF)
9781461474951
Printed ISBN
978-1-4614-7494-4

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