The Immunological Barriers to Regenerative Medicine

1. Mechanisms of Immune Rejection of Stem Cell-Derived Tissues: Insights From Organ Transplantation
Eleanor M. Bolton, J. Andrew Bradley

2. The Immunogenicity of Embryonic Stem Cells and Their Differentiated Progeny
Jeremy I. Pearl, Joseph C. Wu

3. Interaction of Embryonic Stem Cells with the Immune System
Cody A. Koch, Jeffrey L. Platt

4. The Role of NK Cells and T Cells in the Rejection of Embryonic Stem Cell-Derived Tissues
Bob Miyake, Nicholas Zavazava

5. Mitigating the Risk of Immunogenicity in the Pursuit of Induced Pluripotency

Paul J. Fairchild, Naoki Ichiryu

6. Thymic Involution: A Barrier or Opportunity for Cell Replacement Therapy?
Simon Hackett, Paul J. Fairchild

7. Construction of Human Embryonic Stem Cell Banks: Prospects for Tissue Matching
Ge Lin, Qi Ou-Yang, Xiaobing Qian, Guangxiu Lu

8. Generation of Histocompatible Tissues via Parthenogenesis
Paula W. Lampton, Judith A. Newmark, Ann A. Kiessling

9. Prospects for Designing ‘Universal’ Stem Cell Lines
James C. Cicciarelli, Nathan A. Lemp, Noriyuki Kasahara

10. The Immunosuppressive Properties of Adult Stem Cells: Mesenchymal Stem Cells as a Case Study
Francesco Dazzi, Ilaria Marigo

11. The Immunogenicity of Stem Cells and Thymus-Based Strategies to Minimise Immune Rejection
Jessica Morison, Tracy Heng, Ann Chidgey, Richard Boyd

12. The Induction of Mixed Chimerism Using ES Cell-Derived Hematopoietic Stem Cells
Francesca Milanetti, You-Hong Cheng, Richard K. Burt

13. Prospects for the Induction of Transplant Tolerance Using Dendritic Cells
Matthew Buckland, Lesley Smyth, Robert Lechler, Giovanna Lombardi

14. Strategies for the Induction of Tolerance with Monoclonal Antibodies
Luis Graca

15. Induction of Immunological Tolerance to Transgene Products
Brandon K. Sack, David M. Markusic, Roland W. Herzog

16. Addressing the Challenge of Autoimmunity in the Treatment of Diabetes with Stem Cells
Karen English, Kathryn J. Wood

Keywords: Life Sciences, Stem Cells, Immunology, Cell Biology, Biotechnology