RNA Interference from Biology to Therapeutics

1. RNA Interference Pathways and Therapeutic Exploitation
Jesper B. Bramsen, Thomas B. Hansen

2. Synthetic Dicer-Substrate siRNAs as Triggers of RNA Interference
Scott D. Rose, Mark A. Behlke

3. The Role of MicroRNAs in Natural Tissue Development and Application in Regenerative Medicine
Morten Østergaard Andersen, Philipp Dillschneider, Jørgen Kjems

4. Intracellular Delivery Considerations for RNAi Therapeutics
Yu Zhu, Jing Li, David Oupický

5. Mucosal Delivery of RNAi Therapeutics
Borja Ballarín González, Ebbe Bech Nielsen, Troels Bo Thomsen, Kenneth A. Howard

6. Nanomedicines for Systemic Delivery of RNAi Therapeutics
Dan Peer

7. Lipidoids: A Combinatorial Approach to siRNA Delivery
Michael Goldberg

8. Polymeric Micelles for siRNA Delivery
Frederico Pittella, Kazunori Kataoka

9. RNAi Therapeutic Delivery by Exosomes
Samira Lakhal, Samir El Andaloussi, Aisling J. O’Loughlin, Jinghuan Li, Matthew M. J. Wood

10. Aptamer-Mediated siRNA Targeting
Jiehua Zhou, John J. Rossi

11. RNAi as Antiviral Therapy: The HIV-1 Case
Ben Berkhout, Julia J. M. Eekels

12. Genome-Wide RNAi Screening to Identify Human Host Factors Crucial for Influenza Virus Replication
Katharina Ahrens, Alexander Karlas

13. The Application of MicroRNAs in Cancer Diagnostics
Karina D. Sørensen, Marie S. Ostenfeld, Dennis K. Jeppesen, Helle Kristensen, Christa Haldrup, Torben F. Ørntoft

14. Therapeutic Application of MicroRNAs in Cancer
Nobuyoshi Kosaka, Fumitaka Takeshita, Yusuke Yoshioka, Takahiro Ochiya

15. Preclinical and Clinical Studies Employing RNA Interference as a Therapeutic for Respiratory Syncytial Virus (RSV) Infection in the Lung
Amy R. Simon, Verena Karsten, Rachel Meyers, Jeff Cehelsky, Jared Gollob, Akshay Vaishnaw, Sara Nochur

Keywords: Biomedicine, Biomedicine general, Pharmaceutical Sciences/Technology