Advances in Biology and Therapy of Multiple Myeloma

1. Genomic Strategies Determining Progression from MGUS to Multiple Myeloma
Esteban Braggio, Rafael Fonseca

2. Prognostic Implication of Genetic Changes (Cytogenetics, and FISH, Gains and Losses of DNA by SNP Array and aCGH) in Risk Stratification in Myeloma
Jill Corre, Hervé Avet-Loiseau

3. Advances in Multiple Myeloma Gene-Expression Profiling
Saad Usmani, B. Barlogie, J. D. Shaughnessy

4. Growth Factors in Multiple Myeloma
Jérôme Moreaux, Caroline Bret, Karène Mahtouk, Anne-Catherine Sprynski, Dirk Hose, Bernard Klein

5. Role of Wnt Signaling Pathways in Multiple Myeloma Pathogenesis
Mariateresa Fulciniti, Daniel R. Carrasco

6. The mTOR Pathway in Multiple Myeloma
Joseph Gera, Alan Lichtenstein

7. Jak/STAT Signaling in the Pathogenesis and Treatment of Multiple Myeloma
Erik A. Nelson, Sarah R. Walker, David A. Frank

8. The Bone Marrow Microenvironment: Novel Targets to Circumvent Minimal Residual Disease and Drug Resistance in Multiple Myeloma
Kenneth H. Shain, William S. Dalton

9. Osteoclasts: Potential Target for Blocking Microenvironmental Support of Myeloma
Deborah L. Galson, Sonia D’Souza, G. David Roodman

10. Targeting the BAFF/APRIL Cytokine Network in Multiple Myeloma
Stephen A. Mihalcik, Diane F. Jelinek

11. Role of Osteoblast in Myeloma Pathology
Sonia Vallet, Noopur Raje

12. Migration and Homing in Multiple Myeloma
Giada Bianchi, Irene M. Ghobrial

13. Genes and Proteins of Myeloma Endothelial Cells to Search Specific Targets of the Tumor Vasculature
Domenico Ribatti, Angelo Vacca

14. Epigenetic Regulation of Myeloma Within Its Bone Marrow Microenvironment
Elke Bruyne, Ken Maes, Sarah Deleu, Els Valckenborgh, Eline Menu, Isabelle Broek, Joanna Fraczek, Leo Grunsven, Vera Rogiers, Helena Jernberg-Wiklund, Karin Vanderkerken

15. Targeting Multiple Myeloma Tumor Angiogenesis: Focus on VEGF
Klaus Podar, Kenneth C. Anderson

16. Novel In Vivo Models in Myeloma
Eric Sanchez, Haiming Chen, James R. Berenson

Keywords: Biomedicine, Cancer Research, Pharmacology/Toxicology