Pharmacokinetics in Drug Development

1. Modeling Tumor Growth in Oncology
Peter L. Bonate

2. Drug–Drug Interactions: Designing Development Programs and Appropriate Product Labeling
J. Matthew Hutzler, Jack Cook, Joseph C. Fleishaker

3. Modeling the Progression of Disease
Diane R. Mould

4. The Use of Dried Blood Spots for Concentration Assessment in Pharmacokinetic Evaluations
Tapan K. Majumdar, Danny R. Howard

5. Microdosing: Pharmacokinetic and Metabolism Data Early in the Drug Development Process
Graham Lappin

6. Metabolite Testing in Drug Development
Angus N. R. Nedderman, Don K. Walker

7. The -Omics in Drug Development
Majid Y. Moridani, Robyn P. Araujo, Caroline H. Johnson, John C. Lindon

8. Optimal Design of Pharmacokinetic–Pharmacodynamic Studies
Lee-Kien Foo, Stephen B. Duffull

9. Pharmacokinetic Studies in Pregnant Women
Jamie L. Renbarger, David M. Haas

10. Design, Conduct and Analysis of Thorough QT Studies
Tanya Russell, Daniel S. Stein, David J. Kazierad

11. Contribution of Quantitative Whole-Body Autoradioluminography to the Early Selection and Development of Drug Candidates
Alain Schweitzer

12. Pharmacokinetics, Modeling, and Simulation in the Development of Sunitinib Malate: A Case Study
Brett E. Houk, Carlo L. Bello

13. The Clinical Significance of Drug Transporters in Drug Disposition and Drug Interactions
Thomas N. Thompson

Keywords: Biomedicine, Pharmaceutical Sciences/Technology, Biotechnology, Pharmacy, Biochemistry, general