Conjugation and Deconjugation of Ubiquitin Family Modifiers

1. Activation of Ubiquitin and Ubiquitin-Like Proteins
Frederick C. Streich, Arthur L. Haas

2. Control of Ubiquitin Conjugation by Cdc48 and Its Cofactors
Alexander Buchberger

3. Regulation of Ubiquitin Receptors by Coupled Monoubiquitination
Daniela Hoeller, Ivan Dikic

4. Control of Cullin-Ring Ubiquitin Ligase Activity by Nedd8
Raymond J. Deshaies, Ethan D. Emberley, Anjanabha Saha

5. Control of Deneddylation by the COP9 Signalosome
Tilo Schmaler, Wolfgang Dubiel

6. Mechanism, Specificity and Structure of the Deubiquitinases
David Komander

7. Ubiquitin Conjugation and Deconjugation in NF-κB Signaling
Michael Düwel, Kamyar Hadian, Daniel Krappmann

8. Functions of Linear Ubiquitin Chains in the NF-κB Pathway
Kazuhiro Iwai

9. Assembly of K11-Linked Ubiquitin Chains by the Anaphase-Promoting Complex
Michael Rape

10. Ubiquitin Family Members in the Regulation of the Tumor Suppressor p53
Dimitris P. Xirodimas, Martin Scheffner

11. Ubiquitylation in the ERAD Pathway
Frederik Eisele, Antje Schäfer, Dieter H. Wolf

12. Pupylation
Kristin E. Burns, K. Heran Darwin

13. Sumo Control
Katharina Maderböck, Andrea Pichler

14. The In Vivo Functions of Desumoylating Enzymes
Tasneem Bawa-Khalfe, Edward T. H. Yeh

15. Regulatory Functions of Ubiquitin and SUMO in DNA Repair Pathways
Stefan Jentsch, Stefan Müller

16. Sumoylation as a Signal for Polyubiquitylation and Proteasomal Degradation
Maria Miteva, Kirstin Keusekotten, Kay Hofmann, Gerrit J. K. Praefcke, R. Jürgen Dohmen

17. In Vivo Functions of Isgylation
Klaus-Peter Knobeloch

18. Identification and Validation of ISG15 Target Proteins
Larissa A. Durfee, Jon M. Huibregtse

19. FAT10
Christiane Pelzer, Marcus Groettrup

Keywords: Biomedicine, Molecular Medicine