Scleroderma

1. Historical Perspective
Christopher P. Denton, Dame Carol M. Black

2. Therapeutic Evolution: A Professor’s View
Frank Wollheim

3. Overview: Epidemiology, Genetics and Classification
Christopher P. Denton

4. Epidemiology and Environmental Risk Factors
Jammie K. Barnes, Maureen D. Mayes

5. Genetic Factors
Yannick Allanore, Filemon K. Tan

6. Disease Subsets in Clinical Practice
Robyn T. Domsic, Thomas A. Medsger

7. Evolving Concepts of Diagnosis and Classification
Lorinda Chung, Jaap Fransen, Frank H. J. Hoogen

8. Disease Classification Using Molecular Signatures
Michael L. Whitfield, Robert Lafyatis

9. Juvenile Localized Scleroderma
Francesco Zulian

10. Juvenile Systemic Sclerosis
Ivan Foeldvari

11. Scleroderma Mimics
Laura K. Hummers

12. Localized Forms of Scleroderma
Amy E. Gilliam, Anita C. Gilliam

13. Nephrogenic Systemic Fibrosis
Peter J. Wermuth, Sergio A. Jimenez

14. Overview: Pathogenesis Integrated
John Varga

15. Immunological Mechanisms
Francesco Boin, Carlo Chizzolini

16. Innate Immunity
Keith B. Elkon, Julia J. Rhiannon

17. Autoantibodies in Pathogenesis
Kimberly Doering, Antony Rosen

18. The Clinical Aspects of Autoantibodies
John D. Pauling, Neil McHugh

19. Mechanisms of Vascular Disease
Bashar Kahaleh, Mary Jo Mulligan-Kehoe

20. Vascular Biomarkers
Laura K. Hummers

21. Mechanism of Fibrosis
John Varga

22. Fibrosis: Insights from the Stiff Skin Syndrome
Elizabeth E. Gerber, Harry C. Dietz

23. Biomarkers of Fibrosis
Christian Beyer, Oliver Distler, Jörg H. W. Distler

24. Overview of Animal Models
Christopher P. Denton, Robert Lafyatis

25. Overview: Cardiovascular Manifestations and Management
Fredrick M. Wigley

26. Raynaud’s Phenomenon
Fredrick M. Wigley, Ariane L. Herrick

27. Nailfold Capillaroscopy
Maurizio Cutolo, Vanessa Smith

28. Systemic Vascular Disease
Peter Maddison, Marco Matucci-Cerinic

29. Scleroderma Renal Crisis
Christopher P. Denton, Virginia Steen

30. Cardiac Involvement
Sanjiv J. Shah, André Kahan

31. Erectile Dysfunction
Edward V. Lally, Arthur L. Burnett, Trinity J. Bivalacqua

32. Overview: Pulmonary Manifestations and Management
Christopher P. Denton

33. Clinical Assessment of Lung Disease
Gregory J. Keir, Richard M. Silver, Athol U. Wells

34. Computerized Tomography of Interstitial Lung Disease
Athol U. Wells, Jonathan Goldin

35. Treatment of Interstitial Lung Disease
Dinesh Khanna, Donald P. Tashkin

36. Clinical Assessment of Pulmonary Hypertension
Harrison W. Farber, Michael York, Eric Hachulla

37. Treatment of Pulmonary Hypertension
Todd M. Kolb, Paul M. Hassoun

38. Complex Challenges of Pulmonary Hypertension
John Gerard Coghlan

39. Overview: Gastrointestinal Manifestations and Management
Seth Sweetser, Michael Camilleri

40. Upper Gastrointestinal Tract
John O. Clarke, Ikuo Hirano

41. Small and Large Intestinal Involvement
Philip J. Clements, Terri E. Getzug, Dinesh Khanna

42. Evaluation and Management of Skin Disease
Noëlle Starr Sherber

43. Skeletal Muscle Involvement
Andrew L. Mammen

44. Tendons, Joints, and Bone
Jérôme Avouac, Yannick Allanore

45. Pregnancy
Virginia Steen, Eliza F. Chakravarty

46. Overlooked Manifestations
Ami A. Shah

47. Principles of Management
Maureen D. Mayes

48. Immunomodulatory Therapies
Jacob M. Laar

49. Cell-Based Therapies
Alan G. Tyndall, Keith M. Sullivan

50. Investigative Approaches to Drug Therapy
Voon H. Ong, Christopher P. Denton

51. Complementary and Alternate Medicine Approaches
Judy A. Fulop, John Varga

52. Physical and Occupational Therapy
Luc Mouthon, Janet L. Poole

53. Evaluation and Management of Psychosocial Issues
Lisa R. Jewett, Jennifer A. Haythornthwaite, Brett D. Thombs

54. Issues in Clinical Trial Design
Suzanne Kafaja, Daniel E. Furst, Janet E. Pope

55. Measuring Disease Activity and Outcomes in Clinical trials
Dinesh Khanna

56. Patient-Reported Outcomes
Monique Hinchcliff, David Cella

Keywords: Medicine & Public Health, Rheumatology, Internal Medicine, Pneumology/Respiratory System