Cell-Extracellular Matrix Interactions in Cancer

1. The Extracellular Matrix: An Overview
Jeffrey H. Miner

2. Integrin Structure and Function
Manakan Betsy Srichai, Roy Zent

3. Cancer in Context: Importance of the Tumor Microenvironment
Barbara Fingleton, Conor Lynch

4. Basement Membrane Collagens and Cancer
Vadim Pedchenko, Ambra Pozzi

5. Laminins and Cancer Progression
Jerome Jourquin, Manisha Tripathi, Cherise Guess, Vito Quaranta

6. Fibronectins and Their Receptors in Cancer
Christie J. Avraamides, Judith A. Varner

7. Vitronectin-Binding Integrins in Cancer
Eric Murphy, Dwayne Stupack

8. The Function of SPARC in Tumor Cell Biology: SPARC as a Modulator of Cell–Extracellular Matrix Interaction
Rolf A. Brekken, Amy D. Bradshaw

9. Proteoglycans and Cancer
Ralph D. Sanderson, Yang Yang, Anurag Purushothaman, Yekaterina B. Khotskaya, Joseph P. Ritchie, Vishnu C. Ramani

10. Tetraspanins in Cancer
Andries Zijlstra

11. The Role of Integrin-Linked Kinase in Cancer Development and Progression
Paul C. McDonald, Shoukat Dedhar

12. Focal Adhesion Kinase with the Interacting Proteins and Signaling in Cancer
Vita M. Golubovskaya, Elizabeth A. Beierle, Steven N. Hochwald, Elena V. Kurenova, William G. Cance

Keywords: Biomedicine, Cancer Research, Cell Biology, Pharmacology/Toxicology