Phagocytosis of Dying Cells: From Molecular Mechanisms to Human Diseases

Part I. Molecular Mechanisms of Phagocytosis of Dying Cells

1. Molecular Pathways of Different Types of Cell Death: Many Roads to Death
Dmitri V. Krysko, Agnieszka Kaczmarek, Peter Vandenabeele

2. Apoptotic, Autophagic and Necrotic Cell Death Types in Pathophysiological Conditions: Morphological and Histological Aspects
K D’Herde, A Diez-Fraile, T Lammens

3. Role of Attraction and Danger Signals in the Uptake of Apoptotic and Necrotic Cells and its Immunological Outcome
Christoph Peter, Sebastian Wesselborg, Lauber Kirsten

4. Molecules Involved in Recognition and Clearance of Apoptotic/Necrotic Cells
and Cell Debris
Markus Napirei, Hans Georg Mannherz

5. Evolutionarily Conserved Pathways Regulating Engulfment of Apoptotic Cells
Matthew A. Gronski, Kodi S. Ravichandran

6. Innate Apoptotic Immunity: A Potent Immunosuppressive Response Repertoire Elicited by Specific Apoptotic Cell Recognition
David S. Ucker

7. Comparative Characterization of Non-professional and Professional Phagocyte Responses to Apoptotic Cells
Adam Lacy-Hulbert

8. Methods Used to Study Apoptotic Cell Clearance
Uriel Trahtemberg, Dror Mevorach

Part II. Impairment of Phagocytosis of Dying Cells and its Role in the Development of Diseases

9. Results of Defective Clearance of Apoptotic Cells: Lessons from Knock-out Mouse Models
Christopher D. Gregory, John D. Pound

10. Clearance of Dying Cells and Systemic Lupus Erythematosus
Dror Mevorach

11. Apoptotic Cells for Therapy of Transplant Rejection
Sherrie J. Divito, Adrian E. Morelli

12. Impact of Tumour Cell Death on the Activation of Anti-tumour Immune Response
Ji?ina Bart??ková, Radek Špíšek

13. Phagocytosis of Dying Cells in the Pathogenesis of Atherosclerosis
Wim Martinet, Dorien M. Schrijvers, Guido R.Y. Meyer

14. The Impact of Defective Clearance of Apoptotic Cells in the Pathogenesis of Chronic Lung Diseases: Chronic Obstructive Pulmonary Disease, Asthma and Cystic Fibrosis
Paul N. Reynolds, Sandra J. Hodge

15. Environmental Factors Affecting Phagocytosis of Dying Cells:Smoking and Static Magnetic Fields
Luciana Dini, Cristian Vergallo

Keywords: Biomedicine, Biomedicine general, Apoptosis, Immunology, Cancer Research, Rheumatology, Molecular Medicine