The Aetiology of Deep Venous Thrombosis

1. Introduction to the Study of Deep Venous Thrombosis

2. The Coagulation Cascade and the Consensus Model of DVT

3. Hypercoagulability

4. Historical Roots

5. Coagulation and its Disorders: A History of Haematological Research

6. Virchow and the Pathophysiological Tradition in the 19th Century

7. The Pathophysiological Tradition after Virchow

8. Interrupted Circulation: The ‘Stasis’ Hypothesis and the Significance of Venous Valves

9. Underperfusion of Valve Pockets and the Initiation of DVT

10. The Role of Endothelial Hypoxia in DVT

11. The Valve Cusp Hypoxia Hypothesis

12. Molecular Changes in the Hypoxic Endothelium

13. Cadaver Clots or Agonal Thrombi?

DRM-restrictions

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Keywords: MEDICAL / Public Health MED078000