Heat Shock Proteins in Cancer

1. The Hsp90 Chaperone Machinery Acts at Protein Folding Clefts to Regulate Both Signaling Protein Function and Protein Quality Control
William B. Pratt, Yoshihiro Morishima, Yoichi Osawa

2. Implications of Heat Shock Proteins in Carcinogenesis and Cancer Progression
Daniel R. Ciocca, Mariel A. Fanelli, F. Dario Cuello-Carrión, Stuart K. Calderwood

3. HSF1: An Emerging Factor In Cancer
Stuart K. Calderwood, Md Abdul Khaleque, Ajit Bharti, Daniel R. Ciocca

4. Anti-apoptotic, Tumorigenic and Metastatic Potential of Hsp27 (HspB1) and aB-crystallin (HspB5): Emerging Targets for the Development of New Anti-Cancer Therapeutic Strategies
Andre-Patrick Arrigo

5. Heat Shock Protein-27 (Hsp-27) in Breast Cancers: Regulation of Expression and Function
Vishwanie S. Budhram-Mahadeo, Richard J. Heads

6. Role of Heat Shock Protein Hsp25/27 in~the~Metastatic Spread of Cancer Cells
María A. Bausero, Alexzander Asea

7. Heat shock chaperone mortalin and carcinogenesis
Custer C. Deocaris, Sunil C. Kaul, Renu Wadhwa

8. Role of Molecular Chaperones in Cell Senescence
Michael Y. Sherman, Julia Yaglom

9. Involvement of Heat Shock Proteins in Protection of Tumor Cells from Genotoxic Stresses
Cornelia O’Callaghan-Sunol, Vladimir L. Gabai

10. Hsp70 in Tumors: Friend or Foe?
Cristina Bonorino, Ana Paula Souza

11. Hsp70 and Hsp27 as pharmacological targets in apoptosis modulation for cancer therapy
M. Brunet, C. Didelot, S. Subramaniam, A.L. Rérole, A. de Thonel, C. Garrido

12. Heat Shock Protein 90: The Cancer Chaperone
Len Neckers

13. Targeting Hsp90 Function to Treat Cancer: Much More to Be Learned
Luke Whitesell, Catherine A. McLellan

14. Small-molecule Hsp90 Inhibitors: Applications in Cancer and Neurodegenerative diseases
Adeela Kamal Srinivas Kasibhatla, Marco Biamonte, Hong Zhang, Lin Zhang, Karen Lundgren, Marcus F. Boehm, Francis J. Burrows

15. Drugging the Hsp90 molecular chaperone machine for cancer treatment
J.L. Holmes, S.Y. Sharp, P. Workman

16. Cdc37 and protein kinase folding
Robert Matts, Avrom J. Caplan

17. The Elevated Levels of Heat Shock Proteins In Cancer: A Suitable Case For Treatment?
Stuart K. Calderwood, Daniel R. Ciocca, Phillip J. Gray, Nava Zaarur, Stan Lepchammer, Michael Y. Sherman

18. Hsp70-Based Anticancer Vaccines: Chaperoning The Immune Response
Jianlin Gong, Jimmy R. Theriault, Stuart K. Calderwood

19. Piloting of exogenous antigen into cross-presentation pathway by heat shock proteins
Yasuaki Tamura, Goro Kutomi, Jun Oura, Toshihiko Torigoe, Noriyuki Sato

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Keywords: TECHNOLOGY & ENGINEERING / Biomedical TEC059000