Jacobi, Peter A.

Introduction to Heterocyclic Chemistry

Jacobi, Peter A. - Introduction to Heterocyclic Chemistry, ebook


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ISBN: 9781119417675
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A unique approach to a core topic in organic chemistry presented by an experienced teacher to students and professionals

Heterocyclic rings are present in the majority of known natural products, contributing to enormous structural diversity. In addition, they often possess significant biological activity. Medicinal chemists have embraced this last property in designing most of the small molecule drugs in use today. This book offers readers a fundamental understanding of the basics of heterocyclic chemistry and their occurrence in natural products such as amino acids, DNA, vitamins, and antibiotics. Based on class lectures that the author has developed over more than 40 years of teaching, it focuses on the chemistry of such heterocyclic substances and how they differ from carbocyclic systems.

Introductory Heterocyclic Chemistry offers in-depth chapters covering naturally occurring heterocycles; properties of aromatic heterocycles; π-deficient heterocycles; π-excessive heterocycles; and ring transformations of heterocycles. It then offers an overview of 1,3-dipolar cycloadditions before finishing up with a back-to-basics section on nitriles and amidines.

  • Presents a conversational approach to a fundamental topic in organic chemistry teaching
  • Offers a unique look at this core organic chemistry topic via important naturally occurring and/or biologically active heterocycles
  • Based on the author's many years of class lectures for teaching at the undergraduate and graduate level as well as pharmaceutical-industry courses
  • Clear, concise, and accessible for advanced students of chemistry to gain a fundamental understanding of the basics of heterocyclic chemistry

Introductory Heterocyclic Chemistry is an excellent text for undergraduate and graduate students as well as chemists in industrial environments in chemistry, pharmacy, medicinal chemistry, and biology.

Keywords: heterocyclic chemistry; biologically important heterocycles; π-deficient heterocycles; π-excessive heterocycles; dipolar cycloadditions; heterocycles as synthons; ring transformations of heterocycles; nitriles and amidines; biochemistry; molecular biology; organic synthesis; heterocyclic chemistry in amino acids; heterocyclic chemistry in DNA; heterocyclic chemistry in vitamins antibiotics; Introductory Heterocyclic Chemistry, Pharmaceutical & Medicinal Chemistry, Biochemistry (Chemical Biology), Pharmaceutical & Medicinal Chemistry, Biochemistry (Chemical Biology)

John Wiley and Sons, Inc.
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272 pages
Natural Sciences
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