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Chen, Yu-Chie

Time-Resolved Mass Spectrometry: From Concept to Applications

Chen, Yu-Chie - Time-Resolved Mass Spectrometry: From Concept to Applications, ebook

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ISBN: 9781118887356
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Time is an important factor in physical and natural sciences. It characterizes the progress of chemical and biochemical processes. Mass spectrometry provides the means to study molecular structures by detecting gas-phase ions with the unique mass-to-charge ratios. Time-resolved mass spectrometry (TRMS) allows one to differentiate between chemical states that can be observed sequentially at different time points. Real-time mass spectrometric monitoring enables recording data continuously with a specified temporal resolution. The TRMS approaches – introduced during the past few decades – have shown temporal resolutions ranging from hours down to microseconds and beyond.
Thistext covers the key aspects of TRMS. It introduces ion sources, mass analyzers, and interfaces utilized in time-resolved measurements; discusses the influence of data acquisition and treatment; finally, it reviews most prominent applications of TRMS – in the studies of reaction kinetics and mechanism, physicochemical phenomena, protein structure dynamics, biocatalysis, and metabolic profiling.
It will assist science and engineering students to gain a basic understanding of the TRMS concept, and to recognize its usefulness. In addition, it may benefit scientists who conduct molecular studies in the areas of chemistry, physics and biology.

Keywords:

analytical chemistry
biochemistry
chemical analysis
instrumentation
mass spectrometry
molecular dynamics
reaction kinetics
real-time monitoring
temporal resolution
time-resolved measurements

, Mass Spectrometry
Author(s)
 
 
Publisher
John Wiley and Sons, Inc.
Publication year
2016
Language
en
Edition
1
Page amount
376 pages
Category
Natural Sciences
Format
Ebook
eISBN (ePUB)
9781118887356
Printed ISBN
9781118887325

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