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Brandon, Nicholas J.

Cyclic-Nucleotide Phosphodiesterases in the Central Nervous System: From Biology to Drug Discovery

Brandon, Nicholas J. - Cyclic-Nucleotide Phosphodiesterases in the Central Nervous System: From Biology to Drug Discovery, ebook

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ISBN: 9781118836309
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This book reviews advances in understanding phosphodiesterases within the central nervous system and their therapeutic applications. A range of expert authors from both academia and industry describe these, then focus on the areas of greatest scientific and medical interest to provide more detailed coverage. Therapeutic and drug discovery applications are covered for diseases including Alzheimer's, Parkinson's, schizophrenia, erectile dysfunction, and spinal cord injuries. There is also a chapter on drug discovery tools such as in vitro assays and X-ray structures for medicinal chemistry studies.

Keywords: Drug Discovery & Development, phosphodiesterases, cyclic nucleotides, central nervous system, cyclic GMP, cyclic AMP, drug discovery tools, vitro assays, Alzheimer's, Parkinson's, schizophrenia, erectile dysfunction, spinal cord injuries

Author(s)
 
Publisher
John Wiley and Sons, Inc.
Publication year
2014
Language
en
Edition
1
Series
Wiley Series in Drug Discovery and Development
Page amount
400 pages
Category
Natural Sciences
Format
Ebook
eISBN (ePUB)
9781118836309
Printed ISBN
9780470566688

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