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O'Kelly, Michael

Clinical Trials with Missing Data: A Guide for Practitioners

O'Kelly, Michael - Clinical Trials with Missing Data: A Guide for Practitioners, ebook

86,45€

Ebook, ePUB with Adobe DRM
ISBN: 9781118762530
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Printing142 pages with an additional page accrued every 6 hours, capped at 142 pages
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This book provides practical guidance for statisticians, clinicians, and researchers involved in clinical trials in the biopharmaceutical industry, medical and public health organisations. Academics and students needing an introduction to handling missing data will also find this book invaluable.

The authors describe how missing data can affect the outcome and credibility of a clinical trial, show by examples how a clinical team can work to prevent missing data, and present the reader with approaches to address missing data effectively.

The book is illustrated throughout with realistic case studies and worked examples, and presents clear and concise guidelines to enable good planning for missing data. The authors show how to handle missing data in a way that is transparent and easy to understand for clinicians, regulators and patients. New developments are presented to improve the choice and implementation of primary and sensitivity analyses for missing data. Many SAS code examples are included – the reader is given a toolbox for implementing analyses under a variety of assumptions.

Keywords: Clinical Trials, Clinical Trials with Missing Data: A Guide for Practitioners, Michael O'Kelly, Bohdana Ratitch, last observation carried forward, LOCF, mixed models repeated measures, MMRM, multiple imputation approach, MI

Author(s)
 
Publisher
John Wiley and Sons, Inc.
Publication year
2013
Language
en
Edition
1
Series
Statistics in Practice
Page amount
472 pages
Category
Medicine, Health Care, Mode
Format
Ebook
eISBN (ePUB)
9781118762530
Printed ISBN
9781118460702

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