Gill, Jason H.
Anticancer Therapeutics: From Drug Discovery to Clinical Applications
An integrated presentation of the basic science and clinical applications of anticancer agents
Aimed at both undergraduate and postgraduate readers, this unique text provides readers with a fully-integrated presentation of all aspects of the science of anticancer drugs, including their chemistry, pharmacology, and clinical applications.
After heart disease, cancer is the number one killer worldwide, and the tumor microenvironment is forever changing, creating an ever-greater demand for safer, more effective anticancer agents. In response to that demand, the $100 billion cancer drug market continues to grow, with our increased understanding of cancer leading to new drugs being used clinically almost every year.
Anticancer Therapeutics is divided into three sections. Section 1 is an introduction to cancer and therapeutics, and covers the etiology and cellular and molecular basis of cancer. In Section 2, the authors focus on the anticancer agents — their discovery, synthesis, mode of action, mechanisms of resistance, and adverse reactions. Section 3 focuses on specific cancers, explaining how and why the various agents discussed in Section 2 are used, both individually and in combination, to treat different cancers.
- Integrates aspects of basic science, including chemistry and pharmacology and clinical medicine in relation to cancer therapeutics
- Written by an author team comprising specialists in medicinal chemistry, pharmacology, and oncology
- Features full-color images throughout illustrating how drugs bind to cellular targets and exert their pharmacological effect
- Divided into three sections, covering the etiology and cellular and molecular basis of cancer, anticancer agents, and drug applications for different cancers.
Providing the reader with an integrated understanding of all aspects of the science of anticancer agents, this is an ideal textbook for undergraduates studying medicine, nursing, medicinal chemistry, pharmacy, pharmacology and other allied heath / life sciences. It is also a valuable bench reference for pharmacists, medics, and pharmaceutical researchers working in both academia and industry.
Keywords: Pharmacology & Pharmaceutical Medicine, Cell & Molecular Biology, Pharmacology & Pharmaceutical Medicine, Cell & Molecular Biology, anticancer agents; cancer drugs; cancer drug chemistry; cancer drug pharmacochemistry; anticancer therapeutics basic science; anticancer therapeutics chemistry; cancer drug pharmacopeia; anticancer pharmacology; anticancer pharmacology textbook; cancer drug discover; cancer drug clinical applications; small tumor drugs; lung cancer drugs; lymphatic cancer drugs; testicular cancer drugs; ovarian cancer drugs; leukemia drugs; skin cancer drugs; endocrine cancer drugs; exocrine cancer drugs; pancreatic cancer drugs; cancer drug bench reference; neuroblastoma drugs; brain cancer drugs; anticancer therapeutics medicinal chemistry; anticancer therapeutics clinical medicine; anticancer drugs medicinal chemistry; cancer therapeutics; cancer therapeutics safety; cancer therapeutics discovery; cancer therapeutics clinical studies; cancer drug pharmacokinetics; pharmacist guide to cancer drugs
- Author(s)
- Gill, Jason H.
- Groundwater, Paul W.
- Todd, Adam
- Publisher
- John Wiley and Sons, Inc.
- Publication year
- 2015
- Language
- en
- Edition
- 1
- Page amount
- 448 pages
- Category
- Technology, Energy, Traffic
- Format
- Ebook
- eISBN (ePUB)
- 9781118696200
- Printed ISBN
- 9781118622124