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Andrushko, Natalia

Stereoselective Synthesis of Drugs and Natural Products

Andrushko, Natalia - Stereoselective Synthesis of Drugs and Natural Products, ebook

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ISBN: 9781118628331
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Brings together the best tested and proven stereoselective synthetic methods

Both the chemical and pharmaceutical industries are increasingly dependent on stereoselective synthetic methods and strategies for the generation of new chiral drugs and natural products that offer specific 3-D structures. With the publication of Stereoselective Synthesis of Drugs and Natural Products, researchers can turn to this comprehensive two-volume work to guide them through all the core methods for the synthesis of chiral drugs and natural products.

Stereoselective Synthesis of Drugs and Natural Products features contributions from an international team of synthetic chemists and pharmaceutical and natural product researchers. These authors have reviewed the tremendous body of literature in the field in order to compile a set of reliable, tested, and proven methods alongside step-by-step guidance. This practical resource not only explores synthetic methodology, but also reaction mechanisms and applications in medicinal chemistry and drug discovery.

The publication begins with an introductory chapter covering general principles and methodologies, nomenclature, and strategies of stereoselective synthesis. Next, it is divided into three parts:

  • Part One: General Methods and Strategies
  • Part Two: Stereoselective Synthesis by Bond Formation including
    • C-C bond formation
    • C-H bond formation
    • C-O bond formation
    • C-N bond formation
    • Other C-heteroatom formation and other bond formation
  • Part Three: Methods of Analysis and Chiral Separation

References in every chapter serve as a gateway to the literature in the field. With this publication as their guide, chemists involved in the stereoselective synthesis of drugs and natural products now have a single, expertly edited source for all the methods they need.

Keywords: stereoselective synthesis, drug synthesis, asymmetric synthesis, natural products, drug discovery, drug development, chiral drugs, chirality, asymmetric catalysis, synthetic methodology, medicinal chemistry, organic chemistry, reaction mechanisms, laboratory synthesis for natural products, Pharmaceutical & Medicinal Chemistry, Catalysis, Pharmaceutical & Medicinal Chemistry, Catalysis

Author(s)
 
Editor
 
Publisher
John Wiley and Sons, Inc.
Publication year
2013
Language
en
Edition
1
Page amount
1836 pages
Category
Natural Sciences
Format
Ebook
eISBN (PDF)
9781118628331
Printed ISBN
9781118032176

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