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Dickenson, John

Molecular Pharmacology: From DNA to Drug Design

Dickenson, John - Molecular Pharmacology: From DNA to Drug Design, ebook

138,40€

Ebook, ePUB with Adobe DRM
ISBN: 9781118451953
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Printing127 pages with an additional page accrued every 6 hours, capped at 127 pages
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This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology.  Adopting a drug target-based, rather than the traditional organ/system based, approach this innovative guide reflects the current advances and research trends towards molecular based drug design, derived from a detailed understanding of chemical responses in the body.  Drugs are then tailored to fit a treatment profile, rather than the traditional method of ‘trial and error’ drug discovery which focuses on testing chemicals on animals or cell cultures and matching their effects to treatments.

Providing an invaluable resource for advanced under- and post-graduate students, new researchers to the field and practitioners for continuing professional development, Molecular Pharmacology explores; recent advances and developments in the four major human drug target families (G-protein coupled receptors, ion channels, nuclear receptors and transporters), cloning of drug targets, transgenic animal technology, gene therapy,  pharmacogenomics and looks at the role of calcium in the cell. It includes numerous real-world examples and a detailed case-study based chapter  that looks at current and possible future gene therapy treatment strategies for cystic fibrosis. This case study considers the relative merits of both drug therapy for specific classes of mutation and gene therapy to correct the underlying defect.

Keywords: Molecular Biology (Life Sciences)

Author(s)
 
 
 
 
 
Publisher
John Wiley and Sons, Inc.
Publication year
2013
Language
en
Edition
1
Page amount
424 pages
Category
Natural Sciences
Format
Ebook
eISBN (ePUB)
9781118451953
Printed ISBN
9780470684436

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