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Douroumis, Dionysios

Drug Delivery Strategies for Poorly Water-Soluble Drugs

Douroumis, Dionysios - Drug Delivery Strategies for Poorly Water-Soluble Drugs, ebook

152,90€

Ebook, ePUB with Adobe DRM
ISBN: 9781118444672
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Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for administration to patients. Consequently, the development of
techniques and materials to overcome these hurdles is a major area of research in pharmaceutical companies.

Drug Delivery Strategies for Poorly Water-Soluble Drugs provides a comprehensive overview of currently used formulation strategies for hydrophobic drugs, including liposome formulation, cyclodextrin drug carriers, solid lipid nanoparticles, polymeric drug encapsulation delivery systems, self–microemulsifying drug delivery systems, nanocrystals, hydrosol colloidal dispersions, microemulsions, solid dispersions, cosolvent use, dendrimers, polymer- drug conjugates, polymeric micelles, and mesoporous silica nanoparticles. For each approach the book discusses the main instrumentation, operation principles and theoretical background, with a focus on critical
formulation features and clinical studies. Finally, the book includes some recent and novel applications, scale-up considerations and regulatory issues.

Drug Delivery Strategies for Poorly Water-Soluble Drugs is an essential multidisciplinary guide to this important area of drug formulation for researchers in industry and academia working in drug
delivery, polymers and biomaterials.

Keywords: Drug Delivery Strategies for Poorly Water-Soluble Drugs, hydrophobic drugs, liposome formulation, cyclodextrin drug carriers, solid lipid nanoparticles, polymeric drug encapsulation delivery systems, microemulsifying drug delivery systems, nanocrystals, hydrosol colloidal dispersions, microemulsions, solid dispersions, cosolvent use, dendrimers, polymer-drug conjugates, polymeric micelles, mesoporous silica nanoparticles, Biopolymers, Industrial Chemistry, Biopolymers, Industrial Chemistry

Author(s)
 
Publisher
John Wiley and Sons, Inc.
Publication year
2013
Language
en
Edition
1
Series
Advances in Pharmaceutical Technology
Page amount
648 pages
Format
Ebook
eISBN (ePUB)
9781118444672
Printed ISBN
9780470711972

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