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Lue, Neal

Telomerases: Chemistry, Biology and Clinical Applications

Lue, Neal - Telomerases: Chemistry, Biology and Clinical Applications, ebook

124,30€

Ebook, ePUB with Adobe DRM
ISBN: 9781118267516
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Printing105 pages with an additional page accrued every 7 hours, capped at 105 pages
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This book is a comprehensive and up-to-date review and evaluation of the contemporary status of telomerase research.  Chapters in this volume cover the basic structure, mechanisms, and diversity of the essential and regulatory subunits of telomerase.  Other topics include telomerase biogenesis, transcriptional and post-translational regulation, off-telomere functions of telomerase and the role of telomerase in cellular senescence, aging and cancer. Its relationship to retrotransposons, a class of mobile genetic elements that shares similarities with telomerase and serves as telomeres in selected organisms, are also reviewed.

Keywords: Enzymes & Receptors, telomerase structure, telomerase research, telomerase biogenesis, off-telomere functions of telomerase, transcriptional regulation, post-translational regulation, regulatory subunits of telomerase, cellular senescence, aging, cancer

Author(s)
 
Publisher
John Wiley and Sons, Inc.
Publication year
2012
Language
en
Edition
1
Page amount
350 pages
Category
Natural Sciences
Format
Ebook
eISBN (ePUB)
9781118267516
Printed ISBN
9780470592045

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