This book covers the linkage between chronic inflammation and cancer from biochemical, molecular biological, and epidemiological perspectives. The book has 5 sections, which cover a general overview, biochemistry, molecular biology, specific causes, and prevention of inflammation-related cancer. The mechanisms of inflammation-related carcinogenesis described in this book include both common and pathogen-specific mechanisms. Causative factors include infectious (viral and bacterial) diseases like hepatitis, inflammatory diseases like inflammatory bowel disease, and environmental factors like asbestos, nanoparticles, and radiation. In the last section, chapters present future perspectives for cancer prevention and therapeutics against inflammation-mediated cancer.
Keywords: Toxicology, cancer, inflammation, carcinogenesis, chemoprevention, DNA damage, inflammasome, tumor progression, DNA adducts, mechanisms of carcinogenesis, inflammation-related cancer, chronic inflammation