By including clinical models of agonism, indirect drug effects, tolerance, signal transduction, and disease progression, author Sara Rosenbaum has created a work that stands out among introductory-level textbooks in this area.You'll find several features throughout the text to help you better understand and apply key concepts:
Three fictitious drugs are used throughout the text to progressively illustrate the development and application of pharmacokinetic and pharmacodynamic principles
Exercises at the end of each chapter reinforce the concepts and provide the opportunity to perform and solve common dosing problems
Detailed instructions let you create custom Excel worksheets to perform simple pharmacokinetic analyses
Because this is an introductory textbook, the material is presented as simply as possible. As a result, you'll find it easy to gain an accurate, working knowledge of all the core principles, apply them to optimize dosing regimens, and evaluate the clinical pharmacokinetic and pharmacodynamic literature.
Keywords: Clinical Pharmacology & Therapeutics, Foundations of pharmacokinetics, foundations of pharmacodynamics, introduction to pharmacokinetics, introduction to pharmacodynamics, teaching quantitative pharmacokinetics, teaching quantitative pharmacodynamics, impact the dose-response relationship for drugs