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Foundation, Novartis

Fatty Acid and Lipotoxicity in Obesity and Diabetes: Novartis Foundation Symposium

Foundation, Novartis - Fatty Acid and Lipotoxicity in Obesity and Diabetes: Novartis Foundation Symposium, ebook

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ISBN: 9780470985564
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The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects pancreatic β cell function, insulin secretion and lipid synthesis in the liver, and storage in adipose tissue. Maintaining the normal levels of fatty acids requires coordinated regulation between the liver, adipose tissue and skeletal muscle.

This book deals with the molecular aspects of fatty acid action in obesity and insulin resistance. The topics include lipid metabolism and adipose tissue biology, and β cell function and insulin resistance. Chapters deal with the molecular genetics and molecular physiology of energy homeostasis.

Keywords: MEDICAL / Endocrinology & Metabolism MED027000

Author(s)
Publisher
John Wiley and Sons, Inc.
Publication year
2008
Language
en
Edition
1
Series
Novartis Foundation Symposia
Page amount
222 pages
Category
Medicine, Health Care, Mode
Format
Ebook
eISBN (PDF)
9780470985564
Printed ISBN
9780470057643

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