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Foundation, Novartis

Generation and Effector Functions of Regulatory Lymphocytes

Foundation, Novartis - Generation and Effector Functions of Regulatory Lymphocytes, ebook

163,70€

Ebook, PDF with Adobe DRM
ISBN: 9780470871614
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Over the last several years, immunologists have re-discovered the importance of regulatory lymphocytes, formerly termed 'suppressor cells'. Many recent reports have documented their existence, effector functions and potential therapeutic benefits in autoimmunity and transplantation. However, even though modern techniques have allowed us to get a much more detailed picture of these cells, they are still highly controversial. Several unresolved issues responsible for this dilemma are discussed in this book: it is difficult to grow and clone such cells, their phenotypes and effector functions are diverse and can sometimes easily be lost, and it is not well understood how they interact with antigen-presenting cells.

This book contains contributions from leading investigators from around the world, including lively discussion of the current state of the art in studies of regulatory lymphocytes. Topics featured are the physiological control of autoimmunity, the role of antigen-specific cells in various diseases and disease models and effector mechanisms. Therapeutic applications are considered, particularly for type 1 diabetes, tissue transplantation and the control of viral infection. This important and groundbreaking book should be of interest to all immunologists.

Related Novartis Foundation symposia:

254 Immunoinformatics: bioinformatic strategies for better understanding of immune function

Chair: Hans-Georg Rammensee

256 Cancer and inflammation

Chair: Siamon Gordon

Keywords: SCIENCE / Life Sciences / Biochemistry SCI007000

Author(s)
Publisher
John Wiley and Sons, Inc.
Publication year
2004
Language
en
Edition
1
Series
Novartis Foundation Symposia
Page amount
326 pages
Category
Natural Sciences
Format
Ebook
eISBN (PDF)
9780470871614
Printed ISBN
9780470850749

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