Aslanian, Robert G.

Case Studies in Modern Drug Discovery and Development

Aslanian, Robert G. - Case Studies in Modern Drug Discovery and Development, ebook


Ebook, ePUB with Adobe DRM
ISBN: 9781118219676
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Printing158 pages with an additional page accrued every 5 hours, capped at 158 pages
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Learn why some drug discovery and development efforts succeed . . . and others fail

Written by international experts in drug discovery and development, this book sets forth carefully researched and analyzed case studies of both successful and failed drug discovery and development efforts, enabling medicinal chemists and pharmaceutical scientists to learn from actual examples. Each case study focuses on a particular drug and therapeutic target, guiding readers through the drug discovery and development process, including drug design rationale, structure-activity relationships, pharmacology, drug metabolism, biology, and clinical studies.

Case Studies in Modern Drug Discovery and Development begins with an introductory chapter that puts into perspective the underlying issues facing the pharmaceutical industry and provides insight into future research opportunities. Next, there are fourteen detailed case studies, examining:

  • All phases of drug discovery and development from initial idea to commercialization

  • Some of today's most important and life-saving medications

  • Drugs designed for different therapeutic areas such as cardiovascular disease, infection, inflammation, cancer, metabolic syndrome, and allergies

  • Examples of prodrugs and inhaled drugs

  • Reasons why certain drugs failed to advance to market despite major research investments

Each chapter ends with a list of references leading to the primary literature. There are also plenty of tables and illustrations to help readers fully understand key concepts, processes, and technologies.

Improving the success rate of the drug discovery and development process is paramount to the pharmaceutical industry. With this book as their guide, readers can learn from both successful and unsuccessful efforts in order to apply tested and proven science and technologies that increase the probability of success for new drug discovery and development projects.

Keywords: medicinal chemistry, drug discoveries, drug launches, drug discovery process, drug design rationale, drugs and structure-activity relationship development, drugs and absorption-distribution-metabolism-excretion-toxicology, clinical studies and drugs, drugs and CNS, drugs and cardiovascular diseases, drugs and infection, drugs and inflammation, drugs and cancer, drugs and metabolic syndrome, drugs and erectile dysfunction, drugs and osteoporosis, drugs and allergy, Pharmacology & Pharmaceutical Medicine, Organic Chemistry, Pharmacology & Pharmaceutical Medicine, Organic Chemistry

John Wiley and Sons, Inc.
Publication year
Page amount
472 pages
Medicine, Health Care, Mode
Printed ISBN

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