Login

Rosenberg, Michael J.

The Agile Approach to Adaptive Research: Optimizing Efficiency in Clinical Development

Rosenberg, Michael J. - The Agile Approach to Adaptive Research: Optimizing Efficiency in Clinical Development, ebook

79,60€

Ebook, PDF with Adobe DRM
ISBN: 9780470599679
DRM Restrictions

Printing86 pages with an additional page accrued every 9 hours, capped at 86 pages
Copy to clipboard14 excerpts

Apply adaptive research to improve results in drug development

The pharmaceutical industry today faces a deepening crisis: inefficiency in its core business, the development of new drugs. The Agile Approach to Adaptive Research offers a solution. It outlines how adaptive research, using already-available tools and techniques, can enable the industry to streamline clinical trials and reach decision points faster and more efficiently.

With a wealth of real-world cases and examples, author Michael Rosenberg gives readers a practical overview of drug development, the problems inherent in current practices, and the advantages of adaptive research technology and methods. He explains the concepts, principles, and specific techniques of adaptive research, and demonstrates why it is an essential evolutionary step toward improving drug research and development.

Chapters explore such subjects as:

  • The adaptive concept

  • Design and operational adaptations

  • Sample-size reestimation

  • Agile clinical development

  • Safety and dose finding

  • Statistics in adaptive research, including frequentist and Bayesian approaches

  • Data management technologies

  • The future of clinical development


By combining centuries-old intellectual foundations, recent technological advances, and modern management techniques, adaptive research preserves the integrity and validity of clinical research but dramatically improves efficiency.

Keywords: Michnael Rosenberg, Ekins, Sean Ekins, clinical trials, designing clinical trials, managing clinical trials, adaptive design for clinical trials, adaptive research

Author(s)
 
Publisher
John Wiley and Sons, Inc.
Publication year
2010
Language
en
Edition
1
Series
Wiley Series on Technologies for the Pharmaceutical Industry
Page amount
288 pages
Category
Medicine, Health Care, Mode
Format
Ebook
eISBN (PDF)
9780470599679
Printed ISBN
9780470247518

Similar titles